ArticleEinstein (Sao Paulo, Brazil)2026
Mapping the evidence landscape of the oral microbiome-cancer relationship: insights from the 100 most-cited papers.
Article in Einstein (Sao Paulo, Brazil), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to qualitatively and quantitatively analyze the 100 most-cited papers investigating the relationship between the oral microbiome and cancer.
methodsA qualitative and quantitative bibliometric study was conducted to evaluate the 100 most-cited papers on the relationship between cancer and the oral microbiome. The search strategy was applied in the Scopus database. Data related to the articles, authors, and study characteristics were extracted. Descriptive and bivariate analyses were performed.
resultsFrom the 1,033 records retrieved, the 100 most-cited papers in the field were ranked and selected. The most-cited article had accumulated 759 citations. The papers were published between 1998 and 2022; authors from North America and Asia were the most frequent contributors, and reviews were the most common study design. Oral, colorectal, esophageal, and pancreatic cancers were the most frequently investigated cancer sites. Funding was less frequently reported in review articles (OR=0.28; p=0.041) and in papers from Europe (OR=0.14; p<0.001), whereas funding support increased over time (OR=1.05; p=0.037).
conclusionThe most-cited literature indicates substantial research interest in the relationship between cancer and the oral microbiome. The most-cited papers show that this association has been investigated mainly in oral cancer, although associations with cancers at other sites have also been reported. Financial support and international collaboration may help broaden research on this topic.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.