Evidence map›Paper›PMID 42659424›Full record

ReviewBrazilian oral research2026

Clinical myths in dental bleaching: an evidence-based structured narrative review.

Alessandra Reis, Bianca Medeiros Maran, Deisy Cristina Ferreira Cordeiro, Laryssa Mylenna Madruga Barbosa, Renata Maria Oleniki Terra, Alessandro Dourado Loguercio, Michael Willian Favoreto

Abstract readReview
In one paragraph

Review in Brazilian oral research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alessandra ReisUniversidade Estadual de Ponta Grossa - UEPG, Department of Restorative Dentistry, Ponta Grossa, PR, Brazil.ORCID http://orcid.org/0000-0001-6798-2094
Bianca Medeiros MaranUniversidade Estadual de Ponta Grossa - UEPG, Department of Restorative Dentistry, Ponta Grossa, PR, Brazil.ORCID http://orcid.org/0000-0002-1934-6656
Deisy Cristina Ferreira CordeiroUniversidade Estadual de Ponta Grossa - UEPG, Department of Restorative Dentistry, Ponta Grossa, PR, Brazil.ORCID http://orcid.org/0000-0003-4024-4037
Laryssa Mylenna Madruga BarbosaUniversidade Estadual de Ponta Grossa - UEPG, Department of Restorative Dentistry, Ponta Grossa, PR, Brazil.ORCID http://orcid.org/0000-0001-6226-3672
Renata Maria Oleniki TerraUniversidade Estadual de Ponta Grossa - UEPG, Department of Restorative Dentistry, Ponta Grossa, PR, Brazil.ORCID http://orcid.org/0000-0003-1450-9361
Alessandro Dourado LoguercioUniversidade Estadual de Ponta Grossa - UEPG, Department of Restorative Dentistry, Ponta Grossa, PR, Brazil.ORCID http://orcid.org/0000-0001-9880-4856
Michael Willian FavoretoUniversidade Estadual de Ponta Grossa - UEPG, Department of Restorative Dentistry, Ponta Grossa, PR, Brazil.ORCID http://orcid.org/0000-0002-0800-7915

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This narrative review critically examines common myths in dental bleaching that are often presented as strategies to improve efficacy or reduce adverse effects, despite limited, inconsistent, or context-dependent clinical support. The review integrates evidence from clinical trials and systematic reviews identified through searches, with priority given to higher-level clinical evidence when available. In addition, concepts from Evidence-Based Practice and Cognitive Psychology are used to contextualize why weakly supported protocols may persist in clinical decision-making. The analysis addressed frequently disseminated beliefs in clinical practice and led to the following conclusions: a) dietary restriction does not improve bleaching outcomes; b) preventive use of analgesics and/or anti-inflammatory drugs does not reduce tooth sensitivity (TS); c) higher peroxide concentrations may accelerate early bleaching but increase adverse effects and do not enhance final efficacy; d) prolonged gel exposure beyond recommended times does not produce perceptible additional color change and may increase TS; e) tray scalloping does not consistently reduce patient-perceived gingival irritation; f) increasing gel volume or contact area does not improve final bleaching efficacy and may increase biological cost; g) light-activation does not provide additional clinical benefit; h) gel agitation does not enhance bleaching outcomes; i) over-the-counter products do not replace professionally supervised bleaching in terms of predictability and magnitude of color change; and j) desensitizing toothpastes show inconsistent efficacy in preventing TS. Overall, bleaching protocols should be selected according to clinically meaningful benefits, adverse effects, patient-centered outcomes, and the strength and consistency of the available evidence, rather than tradition, intuition, or commercial appeal.

Indexed as

Tooth BleachingTooth Bleaching AgentsDentin SensitivityEvidence-Based DentistryHumansTreatment OutcomeTooth Bleaching Agents

Identifiers

PMID42659424
PMCPMC13502519

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.