ArticleJournal of veterinary internal medicine2026
Seizures and blindness onset zone in 7 horses undergoing radiographic myelography in lateral recumbency under inhalation anesthesia.
Article in Journal of veterinary internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundSeizures and blindness are potential complications associated with myelography. HYPOTHESIS/
objectivesDescribe, classify, and determine onset zone of seizures and blindness in horses undergoing radiographic myelography in lateral recumbency. ANIMALS: Seven young adult horses.
methodsRetrospective study. Horses with seizures or blindness associated with myelography were included.
resultsThree horses with general proprioceptive ataxia and 4 neurologically normal horses (Warmblood = 4, Thoroughbred = 3), ages 9 (range, 3-16) years old. Iohexol (300 mg I/mL) from 50 to 60 mL (0.09-0.1 mL/kg) were administered intrathecally. Six horses had focal facial motor seizures contralateral to the side of recumbency with expansion to generalized seizures in one horse. The seizure onset zone was determined to be the right parietal cortex based on electroencephalography. Absent menace response of the left eye with bilateral normal dazzle and pupillary light reflexes were supportive of cortical blindness (right occipital cortex) in 5 horses. Seizures were managed using short- (diazepam, 3 horses; midazolam, 2; both, 1) and long-term (phenobarbital = 2/6) antiseizure medications with clinical resolution within 2-8 h post-myelogram. Blindness resolved within 8-48 h post-myelogram. CONCLUSIONS AND CLINICAL IMPORTANCE: Contralateral focal facial motor seizures and blindness with an onset zone in the parietal and occipital cerebral cortex, respectively, ipsilateral to the side of recumbency are possible adverse effects with characteristic features in horses undergoing radiographic myelography in lateral recumbency. These signs are transient with full resolution of seizures within hours and up to 2 days for the blindness.
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