Evidence map›Paper›PMID 42658684›Full record

ArticleSTAR protocols2026

Protocol for functional characterization of adult hippocampal neural precursor cells under demyelinating injury conditions in mice.

Shiva Nemati, Soheila Karimi-Abdolrezaee

Abstract read
In one paragraph

Article in STAR protocols, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shiva NematiDepartment of Physiology and Pathophysiology, Manitoba Multiple Sclerosis Research Center, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.
Soheila Karimi-AbdolrezaeeDepartment of Physiology and Pathophysiology, Manitoba Multiple Sclerosis Research Center, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada; Children Hospital Research Institute of Manitoba, Winnipeg, MB, Canada. Electronic address: soheila.karimi@umanitoba.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adult hippocampal neural precursor cells (Hip-NPCs) are highly influenced by brain injury and diseases. Investigating the properties of Hip-NPCs is important for determining their reparative response. Here, we present a protocol for the functional characterization of Hip-NPCs under physiological and demyelinating conditions in adult mice. We describe steps for assessing of Hip-NPC self-renewal, activation state, proliferation, metabolism, and tri-lineage fate commitment. This workflow enables systematic evaluation of how pathological conditions and therapeutic interventions alter Hip-NPC functional states and adaptive responses. For complete details on the use and execution of this protocol, please refer to Nemati et al.

Indexed as

Cell BiologyNeuroscienceStem Cells

Identifiers

PMID42658684
PMCPMC13544388

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.