Evidence map›Paper›PMID 42658588›Full record

Trial reportJournal of consulting and clinical psychology2026

Cognitive rehabilitation and exposure/sorting therapy for hoarding disorder: A randomized controlled trial.

Catherine R Ayers, Jessica J Zakrzewski, Mary E Dozier, Tina Mayes, Michael Thomas, Elizabeth W Twamley, Alexis Carty-Campbell, James Pittman

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of consulting and clinical psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02402647 (Cognitive Rehabilitation and Exposure Therapy for Veterans With Hoarding Disorder), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02402647 nacompletednot on this map

Cognitive Rehabilitation and Exposure Therapy for Veterans With Hoarding Disorder

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2015 to 2023Enrolled115ConditionsHoarding DisorderArmsCognitive Rehabilitation and Exposure/Sorting Treatment (CREST), Exposure Therapy (ET)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Catherine R AyersVA San Diego Healthcare System.
Jessica J ZakrzewskiVA San Diego Healthcare System.ORCID 0000-0002-6821-2603
Mary E DozierDepartment of Psychology, Mississippi State University.
Tina MayesVA San Diego Healthcare System.
Michael ThomasVA San Diego Healthcare System.
Elizabeth W TwamleyVA San Diego Healthcare System.
Alexis Carty-CampbellVA San Diego Healthcare System.
James PittmanVA San Diego Healthcare System.

Funding

FELLOWSHIP IN GERIATRIC MENTAL HEALTHT32MH019934 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Elizabeth W Twamley · 1994 to 2026
$9.5M
Fellowship on Biological Psychiatry and NeuroscienceT32MH018399 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Pei-an (Betty) Shih · 1986 to 2026
$7.3M
Cognitive Rehabilitation and Exposure Therapy for Geriatric HoardingR01MH127056 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Catherine Ayers · 2022 to 2026
$3.5M
CSRD VA I01 CX001149NIMH NIH HHS R01 MH127056NIMH NIH HHS T32 MH018399NIMH NIH HHS T32 MH019934sponsVA Clinical Science Research and DevelopmentVA San Diego Healthcare System
6 · The paper itself

Abstract

objectiveHoarding disorder (HD) is one of the most common and impairing neuropsychiatric conditions in late life. Cognitive Rehabilitation and Exposure/Sorting Therapy (CREST) for HD is effective in reducing HD symptoms and improving functioning when compared with case management. In the current trial (NCT02402647), we compared CREST to a robust control condition, exposure therapy (ET), to determine if CREST provides additional benefit to HD symptom reduction, functioning, and quality of life over ET.

methodOne hundred fifteen Veterans with HD were randomized to receive 26 once weekly, 1-hr manualized individual sessions of CREST (n = 59) or ET (n = 56). CREST included seven sessions of cognitive rehabilitation therapy, while ET included seven sessions of psychoeducation with both groups completing the same manualized ET for 26 sessions. Participants completed assessments at baseline and posttreatment. Outcome measures included assessments of HD symptom severity, functional capacity, self-reported functioning, self-reported disability, and quality of life. Linear mixed-effects models were used to examine change at posttreatment.

resultsParticipants were mostly male (64%) and White/non-Hispanic (72%) and on average were 62 years old with 16 years of education. Participants averaged a 42% improvement in HD symptoms posttreatment (ΔSI-R = 24.3 ± 17.8), but groups did not differ on improvement in HD symptoms, functional capacity, disability, or quality of life. The CREST group reported greater improvements in interpersonal functioning at posttreatment (d = 0.48, p = .012).

conclusionsExposure-based treatment is highly effective for HD. Both CREST and ET groups demonstrated significant reductions in HD symptoms. CREST participants demonstrated additional improvement in self-reported interpersonal functioning. (PsycInfo Database Record (c) 2026 APA, all rights reserved).

Indexed as

Cognitive Behavioral TherapyCognitive TrainingHoarding DisorderImplosive TherapyAgedFemaleHumansMaleMiddle AgedQuality of LifeTreatment OutcomeVeterans

Identifiers

PMID42658588
PMCPMC13523007

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.