ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026
Natural-Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti-Tumor Immunity.
Yuqi Yang, Xiaowei Cai, Xiaoyan Zhong, Tian Qiu, Qinwei Lu, Jiahao Qin, Fei Gong, Yecheng Huang, Chenyu Jiang, Youdong Chen and 2 more
Abstract read
In one paragraphArticle in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
12 authors.
Yuqi YangInstitute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory of Advanced Healthcare Materials & Devices, Biomedical-BasicResearch-Center (BBRC) of Jiangsu Province, Soochow University, Suzhou, China.ORCID https://orcid.org/0009-0004-9224-6987 Xiaoyan ZhongInstitute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory of Advanced Healthcare Materials & Devices, Biomedical-BasicResearch-Center (BBRC) of Jiangsu Province, Soochow University, Suzhou, China.ORCID https://orcid.org/0000-0003-4725-6452 Tian QiuInstitute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory of Advanced Healthcare Materials & Devices, Biomedical-BasicResearch-Center (BBRC) of Jiangsu Province, Soochow University, Suzhou, China.
Qinwei LuInstitute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory of Advanced Healthcare Materials & Devices, Biomedical-BasicResearch-Center (BBRC) of Jiangsu Province, Soochow University, Suzhou, China.
Jiahao QinInstitute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory of Advanced Healthcare Materials & Devices, Biomedical-BasicResearch-Center (BBRC) of Jiangsu Province, Soochow University, Suzhou, China.ORCID https://orcid.org/0000-0002-4313-5242 Fei GongInstitute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory of Advanced Healthcare Materials & Devices, Biomedical-BasicResearch-Center (BBRC) of Jiangsu Province, Soochow University, Suzhou, China.ORCID https://orcid.org/0000-0002-7603-8553 Yecheng HuangInstitute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory of Advanced Healthcare Materials & Devices, Biomedical-BasicResearch-Center (BBRC) of Jiangsu Province, Soochow University, Suzhou, China.
Chenyu JiangInstitute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory of Advanced Healthcare Materials & Devices, Biomedical-BasicResearch-Center (BBRC) of Jiangsu Province, Soochow University, Suzhou, China.
Youdong ChenInstitute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory of Advanced Healthcare Materials & Devices, Biomedical-BasicResearch-Center (BBRC) of Jiangsu Province, Soochow University, Suzhou, China.
Liang ChengInstitute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory of Advanced Healthcare Materials & Devices, Biomedical-BasicResearch-Center (BBRC) of Jiangsu Province, Soochow University, Suzhou, China.ORCID https://orcid.org/0000-0001-5324-9094 Funding
111 ProjectCollaborative Innovation Center of Suzhou Nano Science and TechnologyJoint International Research Laboratory of Carbon-Based Functional Materials and Devices, Macau SAR 0016/2024/RIA1Joint International Research Laboratory of Carbon-Based Functional Materials and Devices, Macau SAR 0064/2024/AMJJoint International Research Laboratory of Carbon-Based Functional Materials and Devices, Macau SAR 0118/2023/RIA2National Natural Science Foundation of China 12372114National Natural Science Foundation of China 32571628National Natural Science Foundation of China 52472288National Natural Science Foundation of China U25A20246Natural Science Foundation of Jiangsu Province BK20250005Natural Science Foundation of Jiangsu Province BK20255001Suzhou Industry Park YZCXPT2023001
6 · The paper itselfAbstract
Immunotherapy has shed light on clinical oncology for several decades. However, it still suffers from heterogeneous therapeutic outcomes and potential immune-related adverse events (irAEs). Inspired by a natural phenomenon that microalgae can absorb and accumulate selenium (Se), a well-known healthcare element, we engineered a Se-enriched cyanobacterium Synechococcus Sp (Se-Ssp) for advanced immunotherapy. Simply by culturing in the presence of Na
Indexed as
bladder cancerimmune checkpoint blockadeimmunotherapymicroalgaeselenium
Identifiers
PMID42658564
PMCPMC13521181
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