Evidence map›Paper›PMID 42658429›Full record

ArticleBiological trace element research2026

Selected Trace Elements in Blood of Women with Preeclampsia in Kongo Central, DR Congo.

A N Malaka, A M Katanga, Y M Tuakashikila, M M Kabamba, M N Nganga, J P Elongi-Moyene, A M Malumba, J K Tuakuila

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Article in Biological trace element research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

A N MalakaFaculty of Sciences and Technologies, University of Kinshasa, Kinshasa, DR, Congo.
A M KatangaFaculty of Sciences and Technologies, University of Kinshasa, Kinshasa, DR, Congo.
Y M TuakashikilaFaculty of Sciences and Technologies, University of Kinshasa, Kinshasa, DR, Congo.
M M KabambaFaculty of Sciences and Technologies, University of Kinshasa, Kinshasa, DR, Congo.
M N NgangaFaculty of Medicine, University of Kinshasa, Kinshasa, DR, Congo.
J P Elongi-MoyeneGeneral Hospital of Kinshasa, Kinshasa, DR, Congo.
A M MalumbaFaculty of Sciences and Technologies, University of Kinshasa, Kinshasa, DR, Congo.
J K TuakuilaFaculty of Sciences and Technologies, University of Kinshasa, Kinshasa, DR, Congo. joel.tuakuila@unikin.ac.cd.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPreeclampsia (PE) is a pregnancy-specific complication affecting 3 to 8% of women worldwide, particularly in developing countries. Environmental factors, including trace elements (TE), have been suggested to be associated with the risk of PE, but with conflicting results depending on the specific elements studied. This study aims to compare blood concentrations of cadmium (Cd), mercury (Hg), manganese (Mn), lead (Pb), and selenium (Se) in women with and without PE.

methodsThe case-control study was conducted (35 cases and 30 controls) in Kongo Central province, in the southwestern of the DR Congo. The logistic regression model was used to estimate the odds ratios of the risk of PE as a function of blood TE levels, after adjusting for potential confounding factors.

resultsHigher blood Cd levels were associated with increased odds of PE in cases as compared to controls [OR = 1.355 (95% CI: 1.077-2.081, P < 0.01]. In contrast, lower blood Se levels were associated with higher odds of PE [OR = 0.097 (95% CI: 0.013-0.394), P < 0.01].

conclusionsThe results of this study highlight a significant association between high blood Cd levels and an increased risk of PE, while high blood Se levels are associated with a reduced risk. Further prospective and interventional studies are warranted to confirm these findings.

Indexed as

DR CongoEnvironmental factorsKimpeseLukalaPreeclampsiaPregnant womenTrace elements

Identifiers

PMID42658429

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.