Evidence map›Paper›PMID 42658264›Full record

ArticlePediatric radiology2026

Completely free-breathing cardiac MRI using deep learning reconstruction reduces sedation and scan time in children.

Aditi Gupta, William Long, Sara Young, Brian Blasiole, Nicholas Mouzakis, Alessandro Scotti, Kyoko Fujimoto, Tarek Alsaied, Mary Schiff, Adam Christopher and 1 more

Abstract read
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In one paragraph

Article in Pediatric radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Aditi GuptaUPMC Children's Hospital of Pittsburgh, 4401 Penn Ave, Pittsburgh, PA, 15224-1334, USA. aditigupta.mamc@gmail.com.
William LongUPMC Children's Hospital of Pittsburgh, 4401 Penn Ave, Pittsburgh, PA, 15224-1334, USA. long7226@gmail.com.
Sara YoungUPMC Children's Hospital of Pittsburgh, 4401 Penn Ave, Pittsburgh, PA, 15224-1334, USA.
Brian BlasioleUPMC Children's Hospital of Pittsburgh, 4401 Penn Ave, Pittsburgh, PA, 15224-1334, USA.
Nicholas MouzakisChildren's National Hospital, Washington, DC, USA.
Alessandro ScottiGE HealthCare, Chicago, IL, USA.
Kyoko FujimotoGE HealthCare, Chicago, IL, USA.
Tarek AlsaiedUPMC Children's Hospital of Pittsburgh, 4401 Penn Ave, Pittsburgh, PA, 15224-1334, USA.
Mary SchiffUPMC Children's Hospital of Pittsburgh, 4401 Penn Ave, Pittsburgh, PA, 15224-1334, USA.
Adam ChristopherUPMC Children's Hospital of Pittsburgh, 4401 Penn Ave, Pittsburgh, PA, 15224-1334, USA.
Laura OlivieriUPMC Children's Hospital of Pittsburgh, 4401 Penn Ave, Pittsburgh, PA, 15224-1334, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTraditional cardiac magnetic resonance (CMR) imaging scan times are long and require breath-holds, often necessitating intubation and mechanical ventilation in young or sick children.

objectiveTo compare CMR duration and anesthesia requirement between highly accelerated single cardiac cycle (1RR) free breathing cine acquisition with deep learning reconstruction and conventional segmented breath-hold cine imaging in pediatric patients. MATERIALS AND

methodsFree breathing with deep learning imaging was used in 150 patients and compared to 150 sequential patients imaged with segmented breath-hold imaging. Specifically, CMR duration, use of anesthesia, anesthesia duration, and emergence time were evaluated. A subgroup analysis was performed on patients less than 35 kg.

resultsCMR duration decreased significantly in the 1RR group (29.2 ± 9.8 min vs 43.0 ± 13.2 min, P<0.01). The use of endotracheal intubation with muscle relaxation during the CMR decreased significantly with free breathing with deep learning sequences for those that required sedation (14% vs 90%, P<0.01), as did anesthesia duration (70.8 ± 24.2 min vs 98.3 ± 26.7 min, P<0.01) and emergence time from anesthesia (15 ± 3.7 min vs 27.1 ± 14.9 min, P<0.01). There was no degradation in contrast-to-noise ratio using blood pool/myocardium contrast difference (534.2 ± 165.1 vs 491.8 ± 165.8, P=0.03). Subanalysis performed on 125 patients (age 12.3 ± 4.1 years) with no significant valve regurgitation confirmed reliable volumetric measurements with free breathing with deep learning given high correlation between both right ventricular cardiac index and main pulmonary artery flow (R=0.92, P<0.001) and left ventricular cardiac index and aorta flow (R=0.84, P<0.001).

conclusionsFree breathing with deep learning single RR acquisition significantly reduces study duration, rates of endotracheal intubation, anesthesia duration, and anesthesia emergence time while maintaining diagnostic image quality and clinical quantitative assessments.

Indexed as

AnesthesiaAortaBreath-holdingChildCongenital heart diseaseDeep learningMagnetic resonanceMyocardium

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.