Evidence map›Paper›PMID 42658142›Full record

ArticleJACC. Asia2026

New-Generation Transcatheter Valves for Extremely Small Aortic Annuli.

Shinichi Shirai, Hirofumi Hioki, Masanori Yamamoto, Kenichi Ishizu, Masaomi Hayashi, Kenji Ando, Takahiro Tokuda, Yusuke Watanabe, Toru Naganuma, Futoshi Yamanaka and 17 more

Abstract read
In one paragraph

Article in JACC. Asia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Shinichi ShiraiDepartment of Cardiology, Kokura Memorial Hospital, Kokura, Japan. Electronic address: shirai440130@gmail.com.
Hirofumi HiokiDepartment of Cardiology, IMS Tokyo Katsushika General Hospital, Tokyo, Japan.
Masanori YamamotoDepartment of Cardiology, Toyohashi Heart Center, Toyohashi, Japan; Department of Cardiology, Nagoya Heart Center, Nagoya, Japan; Department of Cardiology, Gifu Heart Center, Gifu, Japan.
Kenichi IshizuDepartment of Cardiology, Kokura Memorial Hospital, Kokura, Japan.
Masaomi HayashiDepartment of Cardiology, Kokura Memorial Hospital, Kokura, Japan.
Kenji AndoDepartment of Cardiology, Kokura Memorial Hospital, Kokura, Japan.
Takahiro TokudaDepartment of Cardiology, Nagoya Heart Center, Nagoya, Japan.
Yusuke WatanabeDepartment of Cardiology, Teikyo University School of Medicine, Tokyo, Japan.
Toru NaganumaDepartment of Cardiology, New Tokyo Hospital, Matsudo, Japan.
Futoshi YamanakaDepartment of Cardiology, Shonan Kamakura General Hospital, Kamakura, Japan.
Masahiko NoguchiDepartment of Cardiology, Tokyo Bay Urayashu Ichikawa Medical Center, Urayasu, Japan.
Yohei OhnoDepartment of Cardiology, Tokai University School of Medicine, Isehara, Japan.
Tetsuro ShimuraDepartment of Cardiology, Gifu Heart Center, Gifu, Japan.
Fumiaki YashimaDepartment of Cardiology, Saiseikai Utsunomiya Hospital, Tochigi, Japan.
Gaku NakazawaDepartment of Cardiology, Kindai University, Sakai, Japan.
Masahiko AsamiDivision of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan.
Masaki IzumoDepartment of Cardiology, St Marianna University School of Medicine, Kawasaki, Japan.
Hidetaka NishinaDepartment of Cardiology, Tsukuba Medical Center Hospital, Tsukuba, Japan.
Hiroshi UenoDepartment of Cardiology, Toyama University Hospital, Toyama, Japan.
Hiroto SuzuyamaDepartment of Cardiology, Saiseikai Kumamoto Hospital, Kumamoto, Japan.
Kazumasa YamasakiDepartment of Cardiology, Sapporo Higashi Tokushukai Hospital, Hokkaido, Japan.
Kenji NishiokaDepartment of Cardiology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.
Daisuke HachinoheDepartment of Cardiology, Sapporo Heart Center, Sapporo Cardiovascular Clinic, Sapporo, Japan.
Yasushi FukuDepartment of Cardiology, Kurashiki Central Hospital, Okayama, Japan.
Toshiaki OtsukaDepartment of Hygiene and Public Health, Nippon Medical School, Tokyo, Japan; Center for Clinical Research, Nippon Medical School Hospital, Tokyo, Japan.
Kentaro HayashidaDivision of Cardiology, Keio University School of Medicine, Tokyo, Japan.
OCEAN-TAVI Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with extremely small aortic annuli are at increased risk of residual gradients and prosthesis-patient mismatch (PPM) after transcatheter aortic valve replacement (TAVR). Comparative data on contemporary valve platforms in this subset remain limited.

objectivesThe authors aimed to compare early clinical and hemodynamic outcomes among balloon-expandable valves (BEVs), supra-annular self-expanding valves (SA-SEVs), and intra-annular self-expanding valves (IA-SEVs) in patients with severe aortic stenosis and extremely small annuli.

methodsPatients with annular area <314 mm

resultsAmong 385 patients, 125, 136, and 124 underwent BEV, SA-SEV, and IA-SEV implantation, respectively. Effective sample sizes after overlap weighting were 92.4, 93.6, and 85.4, with a median follow-up of 358 days. Adjusted probabilities of severe PPM were similarly low (1.6%, 2.0%, and 2.7%; P = 0.85). mean transvalvular pressure gradient ≥20 mm Hg occurred in 4.5%, 8.3%, and 2.3%, respectively (P = 0.19). PVL ≥mild was numerically more frequent with SEV than BEV (15.8%, 27.3%, and 27.0%; P = 0.09), with adjusted odds ratios versus BEV of 1.92 (95% CI: 0.96-3.84) for SA-SEV and 1.83 (95% CI: 0.91-3.70) for IA-SEV. Major complications and 1-year mortality were similar among groups.

conclusionsContemporary TAVR platforms showed broadly similar early outcomes, although PVL ≥mild was numerically more frequent with self-expanding valves.

Indexed as

extremely small aortic annulinew-generation transcatheter heart valvesOCEAN-TAVI registrypatients-prosthesis mismatchtranscatheter aortic valve replacement

Identifiers

PMID42658142
PMCPMC13654426

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.