Evidence map›Paper›PMID 42657898›Full record

ArticleMicrobiology spectrum2026

Coordinated topoisomerase function shapes the fluoroquinolone response of

Andrew Terrebonne, Caitlynn Diggs, Scot P Ouellette, Leiqiong Gao, Yuk-Ching Tse-Dinh, Li Shen

Abstract read
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Andrew Terrebonne *Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.ORCID 0009-0001-5534-317X
Caitlynn Diggs *Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.
Scot P OuelletteDepartment of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, Nebraska, USA.ORCID 0000-0002-3721-6839
Leiqiong GaoDepartment of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.
Yuk-Ching Tse-DinhBiomolecular Sciences Institute, Department of Chemistry and Biochemistry, Florida International University, Miami, Florida, USA.ORCID 0000-0002-5616-5176
Li ShenDepartment of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA.ORCID 0000-0001-9869-7317

Funding

CRISPR interference of essential stage-specific gene function in Chlamydia trachomatisR21AI175651 · NIAID · LSU HEALTH SCIENCES CENTER · PI SHEN, LI · 2023 to 2024
$429k
NIAID NIH HHS R21 AI175651NIH HHS R21AI175651
6 · The paper itself

Abstract

DNA supercoiling is essential for the developmental cycle of

Indexed as

Anti-Bacterial AgentsChlamydia trachomatisDNA Topoisomerases, Type IFluoroquinolonesMoxifloxacinBacterial ProteinsChlamydia InfectionsDNA, BacterialDNA GyraseDNA ReplicationDNA, SuperhelicalGene Expression Regulation, BacterialHumansAnti-Bacterial AgentsBacterial ProteinsDNA, BacterialDNA GyraseDNA, SuperhelicalDNA Topoisomerases, Type IFluoroquinolonesMoxifloxacinantibiotic toleranceChlamydia trachomatisDNA gyraseDNA replicationDNA supercoilingfluoroquinolone moxifloxacinpersistent formstress adaptationtopAtranscription

Identifiers

PMID42657898
PMCPMC13689479

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.