Evidence map›Paper›PMID 42657478›Full record

ArticleCirculation. Heart failure2026

Transcriptomic Changes Elicited by Semaglutide in Human Ventricular Tissue Support Cell Survival and Lipid Metabolism.

Lilly Underwood, Chun-Sun Jiang, Rohail Bhatti, Gessica de Assis Silva, Ihsan Buker, Ajay Rao, Joao Pereira, Satwik Acharyya, Sunil Karhadkar, David K Crossman and 1 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation. Heart failure, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lilly Underwood *Division of Cardiovascular Diseases, Department of Medicine (L.U., C.-S.J., P.Y.S.), University of Alabama at Birmingham.
Chun-Sun Jiang *Division of Cardiovascular Diseases, Department of Medicine (L.U., C.-S.J., P.Y.S.), University of Alabama at Birmingham.ORCID 0009-0000-3462-213X
Rohail Bhatti *Department of Pharmacology and Physiology, Drexel University College of Medicine, Philadelphia, PA (R.B.).ORCID 0000-0002-9636-0312
Gessica de Assis SilvaDepartment of Neurology (G.A.S., J.P.), University of Alabama at Birmingham.ORCID 0000-0001-6969-7676
Ihsan BukerDepartment of Biostatistics (I.B., S.A.), University of Alabama at Birmingham.ORCID 0009-0008-6020-8715
Ajay RaoSection of Endocrinology, Diabetes, and Metabolism, Lewis Katz School of Medicine at Temple University, Philadelphia, PA (A.R.).ORCID 0000-0002-2550-6097
Joao PereiraDepartment of Neurology (G.A.S., J.P.), University of Alabama at Birmingham.
Satwik AcharyyaDepartment of Biostatistics (I.B., S.A.), University of Alabama at Birmingham.
Sunil KarhadkarDepartment of Surgery, Lewis Katz School of Medicine at Temple University, Birmingham, AL (S.K.).
David K CrossmanDepartment of Genetics (D.K.C.), University of Alabama at Birmingham.ORCID 0000-0002-0981-169X
Priscila Y SatoDivision of Cardiovascular Diseases, Department of Medicine (L.U., C.-S.J., P.Y.S.), University of Alabama at Birmingham.ORCID 0000-0003-0512-7011

Funding

Dysregulation of cardiac signaling in disease and stressR01HL163666 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Priscila Sato · 2022 to 2026
$2.0M
NHLBI NIH HHS R01 HL163666
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cholesterolfatty acidsgene expressionheart transplantationinsulins

Identifiers

PMID42657478
PMCPMC13623079

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.