ArticleClinical interventions in aging2026
Clinical Characteristics and Outcomes of Non-Invasive Ventilation Following Unplanned Extubation in the Elderly ICU Patients: A Retrospective Cohort Study.
Article in Clinical interventions in aging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Unplanned extubation (UE) is a critical adverse event in mechanically ventilated patients in the intensive care unit (ICU). Non-invasive ventilation (NIV) has been used to manage post-extubation respiratory complications; however, evidence regarding its role after UE, particularly in elderly patients, remains limited. This study aimed to characterize NIV use and explore its association with clinical outcomes in elderly ICU patients following UE. Methods: We conducted a retrospective cohort study of UE events in a mixed medical-surgical ICU between 2017 and 2022. Adult patients who experienced UE were included, whereas patients with long-term tracheostomy were excluded. Demographic characteristics, ventilatory conditions, NIV use, and clinical outcomes were analyzed. Multivariable logistic regression was performed to identify factors independently associated with UE failure. Results: A total of 91 UE events were identified. The mean age was 66.3 ± 16.6 years, and 51 patients (56.0%) were elderly. Medical indication for mechanical ventilation (MV) (OR 2.66, 95% CI 1.02-6.94) and higher positive end-expiratory pressure (PEEP) levels (OR 1.36, 95% CI 1.01-1.83) were independently associated with UE failure. Among elderly patients, 13 (25.5%) received NIV after UE. No significant differences were observed in re-intubation rate, duration of mechanical ventilation, or ICU length of stay between elderly patients managed with and without NIV. Findings from the NIV subgroup should be interpreted descriptively because of the limited sample size. Conclusion: Medical admission diagnoses and higher PEEP levels were independently associated with UE failure. Among elderly patients, no clear differences in clinical outcomes were observed between those managed with and without NIV following UE. However, the small NIV subgroup limited definitive conclusions regarding its effectiveness. The role of NIV following UE in elderly ICU patients therefore remains uncertain.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.