Evidence map›Paper›PMID 42657294›Full record

ReviewJournal of oral microbiology2026

Oral dysbiosis: methodological evolution, the mobile resistome and the future of machine learning in dentistry.

Jack Lynch, David Bradshaw, Ricarda Hawkins, Rob Howlin, Sue Pavitt, Thuy Do

Abstract readReview
In one paragraph

Review in Journal of oral microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jack LynchDivision of Oral Biology, School of Dentistry, University of Leeds, Leeds, United Kingdom.
David BradshawHaleon plc, Weybridge, United Kingdom.
Ricarda HawkinsHaleon plc, Weybridge, United Kingdom.
Rob HowlinHaleon plc, Weybridge, United Kingdom.
Sue PavittDivision of Oral Biology, School of Dentistry, University of Leeds, Leeds, United Kingdom.
Thuy DoDivision of Oral Biology, School of Dentistry, University of Leeds, Leeds, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The oral microbiome acts as a significant, yet often overlooked, reservoir for antimicrobial resistance genes (ARGs). This review examines the role of the human resistome in oral health, evaluating current knowledge on the composition, function and dissemination of ARGs within the oral cavity. By comparing conventional culture-based methodologies against recent whole-genome sequencing (WGS) studies, we assess the critical role of the oral‒gut axis in resistance dissemination. The current literature indicates that horizontal gene transfer (HGT) facilitates the spread of mobile genetic elements within oral biofilms. Crucially, oral commensals, such as

Indexed as

biofilmsdrug resistance, microbialgene transfer, horizontalMicrobiotaresistomewhole genome sequencing

Identifiers

PMID42657294
PMCPMC13508494

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.