Optimized Ag enhances antibacterial activity and corrosion resistance of extruded Mg-2Zn-0.2Ca alloy.

Fang Yi, Yi Chen, Dikai Guan, Lingzhi Yang, Junjie Li, Yonghao Gao

Abstract read

In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Fang YiXiangya School of Stomatology, Central South University, Changsha, Hunan 410008, China.

Yi ChenSchool of Materials Science and Engineering, Central South University, Changsha, Hunan 410083, China.

Dikai GuanDepartment of Mechanical Engineering, School of Engineering, University of Southampton, Southampton SO17 1BJ, UK.

Lingzhi YangSchool of Minerals Processing and Bioengineering, Central South University, Changsha, Hunan 410083, China.

Junjie LiSchool of Materials Science and Engineering, Central South University, Changsha, Hunan 410083, China.

Yonghao GaoSchool of Materials Science and Engineering, Central South University, Changsha, Hunan 410083, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infection remains a major cause of implant failure, motivating the development of biodegradable metals with intrinsic antibacterial activity. This study investigated how minor silver (Ag) addition regulates the degradation and antibacterial performance of extruded Mg-2Zn-0.2Ca alloys. Adding 0.1 wt % Ag significantly reduced the degradation rate to 0.14 ± 0.04 mm/y after 672 h of immersion, lower than WE43 (0.66 ± 0.05 mm/y), whereas higher Ag contents accelerated degradation. Extracts from the Ag-free alloy showed moderate antibacterial rates of 43.4% ± 0.06% and 62.4% ± 3.55% against

Indexed as

antibacterial activitybiodegradation behaviorimplant-associated infectionsmagnesium alloysreactive oxygen speciessilver addition

Identifiers

PMID42657292

DOI10.1016/j.isci.2026.117220

PMCPMC13508655

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.