ArticleClinical ophthalmology (Auckland, N.Z.)2026
Modern Hydrophobic Acrylic Intraocular Lens Incorporating HEMA: Three-Month Refractive and Visual Outcomes.
Article in Clinical ophthalmology (Auckland, N.Z.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: To evaluate short-term refractive outcomes, binocular defocus curves, visual phenomena, and intraocular lens (IOL) power calculation accuracy following implantation of the Clareon® monofocal (CNA0T0) IOL. Methods: This was a prospective, single-arm clinical study. The study enrolled consecutive patients without prior ocular surgery or significant ocular pathology. All eyes underwent phacoemulsification and implantation of a CNA0T0 IOL. Primary endpoints were binocular distance and intermediate visual acuity; secondary endpoints included refractive accuracy, binocular defocus curves, visual phenomena, and IOL glistenings. Outcomes were measured up to 3 months postoperatively-sufficient to assess early refractive stability. Results: Fifty participants (90 eyes) were enrolled, and 44 participants (88 eyes) completed the study. At 3 months, binocular distance-corrected defocus curves demonstrated favorable intermediate visual performance, with a mean visual acuity of 0.10 logMAR at -1.50 D (66 cm) and 0.30 logMAR at -2.50 D (40 cm). Dysphotopsias were infrequent, no IOL glistenings were observed on slit-lamp or SD-OCT examination during the 3-month follow-up, and cystoid macular edema occurred in 3 eyes (3.4%) at 1 month. The mean spherical equivalent at 3 months was -0.25 ± 0.38 D in myopic eyes, -0.09 ± 0.44 D in emmetropic eyes, and -0.10 ± 0.42 D in hyperopic eyes, with 82-85% of eyes within ±0.50 D of the target refraction. Conclusions: The CNA0T0 IOL demonstrated favorable short-term refractive accuracy and binocular functional intermediate visual outcomes, with minimal dysphotopsia and no glistenings detected at 3 months. The Barrett Universal II and Hoffer QST formulas provided accurate refractive predictions across refractive subgroups in this cohort.
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