Evidence map›Paper›PMID 42657093›Full record

ReviewMedComm2026

Mitochondria as the Hub of Apoptosis: A Comprehensive Insight From Mitochondria to Interactions With Other Organelles.

Rubin Tan, Jinming Zhao, Rong Wang, Yue Shi, Zaozao Chen, Yixuan Ma, Na Li, Wenqing Duan, Duo Lin, Chunxiang Zhang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in MedComm, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rubin TanDepartment of Physiology School of Basic Medical Sciences Southwest Medical University Luzhou China.ORCID https://orcid.org/0000-0002-1513-5616
Jinming ZhaoDepartment of Pathology College of Basic Medical Sciences China Medical University Shenyang China.
Rong WangDepartment of Cardiology, West China Hospital Sichuan University Chengdu China.
Yue ShiDepartment of Physiology School of Basic Medical Sciences Xuzhou Medical University Xuzhou China.
Zaozao ChenCollege of Life Sciences Xuzhou Medical University Xuzhou China.
Yixuan MaFirst Clinical Medical School Xuzhou Medical University Xuzhou China.
Na LiDepartment of Physiology School of Basic Medical Sciences Southwest Medical University Luzhou China.
Wenqing DuanFirst Clinical Medical School Xuzhou Medical University Xuzhou China.
Duo LinFirst Clinical Medical School Xuzhou Medical University Xuzhou China.
Chunxiang ZhangDepartment of Physiology School of Basic Medical Sciences Southwest Medical University Luzhou China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apoptosis is a core program regulating organismal homeostasis and plays a pivotal role in the onset and progression of most diseases. Increasing evidence in recent years indicates that mitochondria are not only central to cellular metabolism but also play a pivotal role in regulating apoptosis. However, no systematic review elucidating how mitochondria finely regulate apoptotic processes through multidimensional mechanisms, including apoptosis-resistant diseases such as cancer. This paper systematically summarizes the molecular mechanisms by which mitochondria mediate apoptosis. We focus on the regulation of cytochrome

Indexed as

apoptosisMAMmitochondriamitochondrial autophagymitochondrial transplantationMOMPmtDNA

Identifiers

PMID42657093
PMCPMC13507834

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.