SynthesisFrontiers in cardiovascular medicine2026
Global research trends and hotspots of bioresorbable occluders for congenital heart disease: a bibliometric analysis.
Synthesis in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Bioresorbable occluders have become an important research direction in the interventional treatment of congenital heart disease. Existing reviews have mainly synthesized materials, device designs, and experimental or clinical outcomes, whereas the field's global research structure and temporal evolution remain insufficiently quantified. This study therefore aimed to map research on bioresorbable occluders for congenital heart disease from 2006 to 2026, including its publication trajectory, collaborative structure, knowledge base, thematic evolution, and emerging fronts. Methods: We searched the Web of Science Core Collection and Scopus databases for related publications from January 2006 to May 2026, limiting document types to articles and reviews and language to English. Bibliometric analysis and visualization were performed using Bibliometrix (R package), VOSviewer, and CiteSpace. Analytic dimensions included annual publication trends, country/region collaboration networks, institutional distribution, journal output, highly cited articles, author collaboration networks, keyword co-occurrence and burst detection, and LDA topic modeling. Results: A total of 105 publications were included. Annual publication output exhibited marked year-to-year fluctuations, with a local increase during 2009-2012 and renewed, although variable, research activity after 2021; the highest annual output was recorded in 2025 ( Conclusion: Research on bioresorbable occluders for congenital heart disease is accelerating from technical validation toward clinical translation, with China showing prominent representation in the affiliation-derived country distribution and occupying a central position in the international collaboration network. Research attention has expanded from conventional septal occlusion and catheter-based procedures toward bioresorbable materials and devices, degradation and mechanical performance, endothelialization, tissue regeneration, and advanced manufacturing. Recent attention to multicenter evaluation, residual shunt, and migraine further suggests increasing interest in clinical translation and post-closure outcomes. Future research should emphasize the biomechanical coupling mechanisms between degradation kinetics and tissue repair, integrated intelligent functional design, and construction of long-term real-world data risk assessment systems. Deep interdisciplinary integration and global collaborative innovation are expected to drive the vision of intervention without permanent implants and definitive healing toward realization in this field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.