Evidence map›Paper›PMID 42657006›Full record

Observational studyResearch and practice in thrombosis and haemostasis2026

Outcomes of catheter-directed mechanical thrombectomy in patients with cancer-associated pulmonary embolism: a multicenter, prospective registry.

Marta Banaszkiewicz, Sylwia Sławek-Szmyt, Jakub Stępniewski, Paweł Kurzyna, Aneta Klotzka, Wiktor Kuliczkowski, Jacek Klaudel, Maciej Lewandowski, Marek Grabka, Marek Roik and 9 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Research and practice in thrombosis and haemostasis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Marta BanaszkiewiczDepartment of Pulmonary Circulation, Thromboembolic Diseases and Cardiology, Centre of Postgraduate Medical Education, European Reference Lung Member, European Health Centre Otwock, Otwock, Poland.
Sylwia Sławek-SzmytDepartment of Cardiology, Poznan University of Medical Sciences, Poznan, Poland.
Jakub StępniewskiPulmonary Circulation Centre, Department of Cardiac and Vascular Disease, Jagiellonian University Medical College, John Paul II Hospital, Krakow, Poland.
Paweł KurzynaDepartment of Pulmonary Circulation, Thromboembolic Diseases and Cardiology, Centre of Postgraduate Medical Education, European Reference Lung Member, European Health Centre Otwock, Otwock, Poland.
Aneta KlotzkaDepartment of Cardiology, Poznan University of Medical Sciences, Poznan, Poland.
Wiktor KuliczkowskiDepartment of Cardiology, Wroclaw Medical University, Wroclaw, Poland.
Jacek KlaudelDepartment of Cardiology, St. Adalbert's Hospital, Copernicus PL, Gdansk, Poland.
Maciej LewandowskiDepartment of Cardiology, Pomeranian Medical University, Szczecin, Poland.
Marek Grabka1st Department of Cardiology, Silesian Medical University, Upper Silesian Medical Centre, Katowice, Poland.
Marek RoikDepartment of Internal Medicine and Cardiology, Medical University of Warsaw, Warsaw, Poland.
Marcin WaligóraPulmonary Circulation Centre, Department of Cardiac and Vascular Disease, Jagiellonian University Medical College, John Paul II Hospital, Krakow, Poland.
Ewa MroczekDepartment of Cardiology, Wroclaw Medical University, Wroclaw, Poland.
Michał ŁomiakDepartment of Pulmonary Circulation, Thromboembolic Diseases and Cardiology, Centre of Postgraduate Medical Education, European Reference Lung Member, European Health Centre Otwock, Otwock, Poland.
Szymon DarochaDepartment of Pulmonary Circulation, Thromboembolic Diseases and Cardiology, Centre of Postgraduate Medical Education, European Reference Lung Member, European Health Centre Otwock, Otwock, Poland.
Zbigniew KrasińskiDepartment of Vascular Surgery, Poznan University of Medical Sciences, Poznan, Poland.
Adam TorbickiDepartment of Pulmonary Circulation, Thromboembolic Diseases and Cardiology, Centre of Postgraduate Medical Education, European Reference Lung Member, European Health Centre Otwock, Otwock, Poland.
Grzegorz KopećPulmonary Circulation Centre, Department of Cardiac and Vascular Disease, Jagiellonian University Medical College, John Paul II Hospital, Krakow, Poland.
Aleksander AraszkiewiczDepartment of Cardiology, Poznan University of Medical Sciences, Poznan, Poland.
Marcin KurzynaDepartment of Pulmonary Circulation, Thromboembolic Diseases and Cardiology, Centre of Postgraduate Medical Education, European Reference Lung Member, European Health Centre Otwock, Otwock, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cancer-associated pulmonary embolism (PE) is a commonplace complication that contributes to morbidity and mortality. Data of catheter-directed mechanical thrombectomy (CDMT) in patients with cancer are limited. Objectives: To assess the efficacy and safety of CDMT in patients with intermediate-high or high-risk PE and cancer comorbidity. Methods: Multicenter prospective, observational study of 290 PE patients treated with CDMT using continuous vacuum aspiration thrombectomy systems. Patients were classified into 2 groups: oncologic patients (OP) and nononcologic patients (NOP). The primary safety endpoints included in-hospital all-cause mortality and procedure-related major bleeding. The primary efficacy endpoint was the change in right-to-left-ventricle (RV/LV) ratio before and 48 hours after CDMT. The efficacy and safety of CDMT were compared between OP and NOP. Results: Active cancer was observed in 18.3% (53/290) of patients with PE treated with CDMT. OP did not differ significantly from NOP in terms of baseline characteristics. After treatment, both OP and NOP demonstrated RV/LV ratio reduction by 27% (the mean change of -0.37 ± 0.22 ( Conclusions: CDMT in OP characterized an acceptable safety profile and substantial improvement in RV function, similar to those observed in NOP. Patients with cancer-related PE had similar in-hospital survival rate compared with patients without cancer, when treated with CDMT.

Indexed as

NeoplasmsPulmonary EmbolismRegistriesThrombectomyAgedAged, 80 and overFemaleHemorrhageHospital MortalityHumansMaleMiddle AgedProspective StudiesRisk FactorsTreatment Outcomecancercancer-associated thrombosiscatheter-directed mechanical thrombectomymechanical thrombectomypulmonary embolismsafety

Identifiers

PMID42657006
PMCPMC13508647

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.