Evidence map›Paper›PMID 42656896›Full record

ReviewJACS Au2026

The Power of Tiny Spaces.

A Andrieu-Brunsen, O Azzaroni, H Binyaminov, A Danil de Namor, M Fyta, J García-Martínez, S Guldin, S Howorka, S Lamotte, S G Lemay and 16 more

Abstract readReview
In one paragraph

Review in JACS Au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

A Andrieu-BrunsenErnst-Berl Institut Für Technische und Makromolekulare Chemie, Technische Universität Darmstadt, Peter-Grünberg-Straße 8, Darmstadt 64287, Germany.ORCID https://orcid.org/0000-0002-3850-3047
O AzzaroniInstituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas (INIFTA), CONICET, and Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, CC16, Suc. 4, La Plata 1900, Buenos Aires, Argentina.ORCID https://orcid.org/0000-0002-5098-0612
H BinyaminovColloid Chemistry Department, Max Planck Institute of Colloids and Interfaces, Am Mühlenberg 1, Potsdam 14476, Germany.
A Danil de NamorSchool of Chemistry & Chemical Engineering, FEPS, University of Surrey, Guildford, Surrey GU2 7XH, U.K.
M FytaComputational Biotechnology, RWTH Aachen University, Worringerweg 3, Aachen 52074, Germany.ORCID https://orcid.org/0000-0002-5425-7907
J García-MartínezLaboratorio de Nanotecnología Molecular, Departamento de Química Inorgánica, Universidad de Alicante, Ctra. San Vicente-Alicante s/n, Alicante 03690, Spain.ORCID https://orcid.org/0000-0002-7089-4973
S GuldinTechnical University of Munich, School of Life Sciences, Freising, Germany, TUMCREATE Ltd, 1 CREATE Way, Singapore 138602, Singapore.
S HoworkaDepartment of Chemistry & Institute of Structural Molecular Biology, University College London, London WC1H 0AJ, U.K.ORCID https://orcid.org/0000-0002-6527-2846
S LamotteAnalytical and Material Science, BASF SE, Ludwigshafen am Rhein 67056, Germany.
S G LemayHuygens-Kamerlingh Onnes Laboratory, Leiden Institute of Physics Leiden University, Niels Bohrweg 2 2333 CA, The Netherlands.ORCID https://orcid.org/0000-0002-0404-3169
B V LotschMax Planck Institute for Solid State Research, Heisenbergstraße 1, Stuttgart 70569, Germany.ORCID https://orcid.org/0000-0002-3094-303X
S MagdassiInstitute of Chemistry, the Hebrew University of Jerusalem, Jerusalem 91904, Israel.ORCID https://orcid.org/0000-0002-6794-0553
K NakanishiInstitute of Materials and Systems for Sustainability, Nagoya University, Nagoya 464-8601, Japan.
C PluegSusonity Commercial GmbH, Industriepark Hoechst G875, Frankfurt D-65929, Germany.
S PolarzLeibniz-University Hannover Chair for Inorganic Chemistry: Molecular and Material Science, Callinstrasse 9, Hannover 30167, Germany.ORCID https://orcid.org/0000-0003-1651-4906
L PozzoDepartment of Chemical Engineering, Molecular Engineering and Sciences Institute, and Department of Human Centered Design and Engineering, University of Washington, Seattle, Washington 98195-1750, United States.ORCID https://orcid.org/0000-0001-7104-9061
M RaftiInstituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas (INIFTA), CONICET, and Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, CC16, Suc. 4, La Plata 1900, Buenos Aires, Argentina.ORCID https://orcid.org/0000-0003-3393-358X
M RehahnErnst-Berl Institut Für Technische und Makromolekulare Chemie, Technische Universität Darmstadt, Peter-Grünberg-Straße 8, Darmstadt 64287, Germany.
A G RothNanostone Water GmbH, Am Bahndamm 12, Halberstadt 38820, Germany.
C SanchezInstitute for Advanced Study, University of Strasbourg, Strasbourg 67083, France.ORCID https://orcid.org/0000-0002-6426-4844
D A ScherlisDepartamento de Química Inorgánica, Analítica y Química Física/INQUIMAE, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires C1428EHA, Argentina.ORCID https://orcid.org/0000-0002-0588-287X
G J A A Soler-IlliaInstituto de Nanosistemas, Escuela de Bio y Nanotecnologías, (INS-EByN-UNSAM-CONICET), Av. 25 de Mayo 1169, San Martín 1650, Argentina.ORCID https://orcid.org/0000-0001-9984-3806
I SzleiferDepartment of Biomedical Engineering and Department of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.ORCID https://orcid.org/0000-0002-8708-0335
K TschulikLehrstuhl Für Analytische Chemie, Ruhr-Universität Bochum, Universitätsstr, Bochum 44801, Germany.ORCID https://orcid.org/0000-0001-7637-4082
M ThommesDepartment of Chemical and Biological Engineering, Friedrich-Alexander-University Erlangen-Nürnberg, Egerlandstr. 3, Erlangen 91058, Germany.ORCID https://orcid.org/0000-0002-3702-4976
E Toimil-MolaresMaterials Research Department, GSI Helmholtz Centre for Heavy Ion Research and Materials and Geosciences Department, Technical University of Darmstadt, Darmstadt 64287, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Confined spaces at the nanoscale  pores, channels, and cavities that alter molecular affinities and restrict molecular motion, orientation and local distribution  are emerging as a powerful design principle for next-generation materials. By tailoring the structure and functionality of these confined spaces, it is possible to control reactivity, transport, and material properties in ways that are unattainable in bulk systems. This Perspective highlights nanoconfinement as a unifying principle for programming function and addressing major societal challenges in energy, water, health and sustainability. Drawing inspiration from nature's remarkable precision in bio-molecular control, we showcase six representative areas in which confined spaces are transforming technology: chromatography, catalysis, nanofluidics, bioinspired pore design, confinement-programmed material states, and data-driven material development. Together, these examples illustrate the power of nanoconfinement as an enabling unifying concept. By integrating orthogonal functionalization strategies, advanced characterization, modeling, and digitalization, programmable nanoconfinement will become a versatile framework for engineering materials and processes that meet the demands of a sustainable and technologically advanced society.

Indexed as

bioinspired materialscatalysisconfinementdata-driven material designenergymedicinenanofluidicsnanoporeseparationsustainability

Identifiers

PMID42656896
PMCPMC13508101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.