Evidence map›Paper›PMID 42656890›Full record

ArticleChemical & biomedical imaging2026

Label-Free Hyperspectral Raman Imaging and Analysis of a 3D Spheroid Model for Liver Fibrosis Study.

Gunganist Kongklad, Menglu Li, Tomoko Yamashita, Tomoaki Okumura, Satoshi Fujita, Katsumasa Fujita

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical & biomedical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gunganist KongkladDepartment of Applied Physics, Graduate School of Engineering, The University of Osaka, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Menglu LiDepartment of Applied Physics, Graduate School of Engineering, The University of Osaka, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.ORCID https://orcid.org/0000-0003-2223-1881
Tomoko YamashitaDepartment of Applied Physics, Graduate School of Engineering, The University of Osaka, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Tomoaki OkumuraDepartment of Applied Physics, Graduate School of Engineering, The University of Osaka, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Satoshi FujitaAdvanced Photonics and Biosensing Open Innovation Laboratory, National Institute of Advanced Industrial Science and Technology (AIST), 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.ORCID https://orcid.org/0000-0002-1139-7002
Katsumasa FujitaDepartment of Applied Physics, Graduate School of Engineering, The University of Osaka, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.ORCID https://orcid.org/0000-0002-2284-375X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An aberrant wound-healing response to chronic liver injury results in excessive accumulation of extracellular matrix proteins, including collagen, leading to liver fibrosis, a process in which hepatocytes and hepatic stellate cells (HSCs) play key roles. In this study, we present HepG2 and LX-2 cocultured spheroids as a three-dimensional

Indexed as

3D coculture modelextracellular matrixfree fatty acidhyperspectral Raman imagingliver fibrosistransforming growth factor-β

Identifiers

PMID42656890
PMCPMC13508106

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.