Evidence map›Paper›PMID 42656535›Full record

ArticleEClinicalMedicine2026

Clearance of

Janet M Towns, Janath A Fernando, Rebecca Wigan, Marcelina Krysiak, David A Lewis, Rick Varma, Anna McNulty, Deborah A Williamson, Carole Khaw, Jayne Howard and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EClinicalMedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Janet M TownsMelbourne Sexual Health Centre, Bayside Health, Melbourne, Victoria, Australia.
Janath A FernandoDepartment of Infectious Diseases at The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.
Rebecca WiganMelbourne Sexual Health Centre, Bayside Health, Melbourne, Victoria, Australia.
Marcelina KrysiakDepartment of Infectious Diseases at The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.
David A LewisWestern Sydney Sexual Health Centre, Western Sydney Local Health District, Parramatta, New South Wales, Australia.
Rick VarmaSydney Sexual Health Centre, Sydney, New South Wales, Australia.
Anna McNultySydney Sexual Health Centre, Sydney, New South Wales, Australia.
Deborah A WilliamsonDepartment of Infectious Diseases at The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.
Carole KhawAdelaide Sexual Health Centre, Infectious Diseases Unit, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Jayne HowardMelbourne Sexual Health Centre, Bayside Health, Melbourne, Victoria, Australia.
Kate PotappelMelbourne Sexual Health Centre, Bayside Health, Melbourne, Victoria, Australia.
Louise OwenStatewide Sexual Health Service, Hobart, Tasmania, Australia.
Caroline ThngGold Coast Sexual Health, Southport, Queensland, Australia.
Nathan RyderPacific Clinic, Newcastle Sexual Health, Hunter New England Local Health District, New South Wales, Australia.
Mitchell HicksonWestern Sydney Sexual Health Centre, Western Sydney Local Health District, Parramatta, New South Wales, Australia.
Eric P F ChowMelbourne Sexual Health Centre, Bayside Health, Melbourne, Victoria, Australia.
Christopher K FairleyMelbourne Sexual Health Centre, Bayside Health, Melbourne, Victoria, Australia.
Stephen R GravesAustralian Rickettsial Reference Laboratory, Barwon Health, Geelong, Victoria, Australia.
Jason J OngMelbourne Sexual Health Centre, Bayside Health, Melbourne, Victoria, Australia.
Sarah HuffamBarwon Reproductive and Sexual Health Clinic, University Hospital, Barwon Health, Geelong, Victoria, Australia.
Shivani PasrichaDepartment of Infectious Diseases at The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.
Marcus Y ChenMelbourne Sexual Health Centre, Bayside Health, Melbourne, Victoria, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Syphilis is increasing worldwide, and secondary syphilis may represent its most infectious stage. Scarce data exist on Methods: Men-who-have-sex-with-men (MSM) and transgender women with secondary syphilis were recruited from Australian clinics between January 27, 2023, and August 19, 2024. Oral, anal or genital lesions were swabbed, and non-lesion samples (blood, oral cavity and anal canal swabs were collected on the day of treatment (baseline). Non-lesion oral cavity and anal canal swabs were repeated 3, 7, 14 and 30 days post-treatment. Findings: 78 cis-men and one trans-woman, who reported sex with men, were included. At baseline, Interpretation: During secondary syphilis, most MSM had Funding: Australian National Health and Medical Research Council.

Indexed as

AnalClearanceOralSyphilisTreponema pallidum

Identifiers

PMID42656535
PMCPMC13506794

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.