Evidence map›Paper›PMID 42656530›Full record

ArticleFrontiers in medicine2026

Efficacy, safety, and transcriptomic mechanisms of Fuzheng Yangxin formula for enhanced recovery after coronary artery bypass grafting: a propensity score-matched prospective cohort study.

Jinyang Yu, Yifei Wang, Yunhu Li, Tong Ding, Luyu Meng, Xiaochang Ma, Yunpeng Ling, Yichen Gong

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06961136 (Prospective Cohort Study on Fuzheng Yangxin Prescription For Rapid Rehabilitation of Patients With Qi-Yin Deficiency Syndrome After Coronary Artery Bypass Grafting), which is not on this map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06961136 recruitingnot on this map

Prospective Cohort Study on Fuzheng Yangxin Prescription For Rapid Rehabilitation of Patients With Qi-Yin Deficiency Syndrome After Coronary Artery Bypass Grafting

TypeobservationalSponsorPeking University Third HospitalRan2025 to 2026Enrolled300ConditionsCoronary Artery BypassArmsFuzheng Yangxin prescription, placebo
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jinyang Yu *Department of Cardiac Surgery, Peking University Third Hospital, Beijing, China.
Yifei Wang *Department of Cardiovascular Disease, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Yunhu LiDepartment of Traditional Chinese Medicine, Peking University Third Hospital, Beijing, China.
Tong DingDepartment of Cardiac Surgery, Peking University Third Hospital, Beijing, China.
Luyu MengDepartment of Cardiac Surgery, Peking University Third Hospital, Beijing, China.
Xiaochang MaDepartment of Cardiovascular Disease, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Yunpeng LingDepartment of Cardiac Surgery, Peking University Third Hospital, Beijing, China.
Yichen GongDepartment of Cardiac Surgery, Peking University Third Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aimed to evaluate the clinical efficacy, safety, and transcriptomic mechanisms of Fuzheng Yangxin Formula (FZYX) for enhanced recovery after coronary artery bypass grafting (CABG) in patients with Qi-Yin deficiency syndrome. Methods: This prospective cohort study utilized 1:1 propensity score matching (PSM). Matched patients ( Results: Post-intervention, the FZYX group demonstrated significantly lower peak Cr (68.50 vs. 74.50 μmol/L, unadjusted Conclusion: FZYX appears to be a safe and promising adjunctive therapy post-CABG. While the primary endpoint was formally negative, exploratory analyses suggest it may provide target organ protection and stable physical recovery, potentially associated with modulating macrophage/monocyte-driven innate inflammation, promoting adaptive immune reconstitution, and accelerating tissue repair. Clinical trial registration: Identifier NCT06961136, https://clinicaltrials.gov/study/NCT06961136.

Indexed as

coronary artery bypass graftingenhanced recovery after surgery (ERAS)Fuzheng Yangxin formulaimmune microenvironmentpropensity score matchingtranscriptome sequencing

Identifiers

PMID42656530
PMCPMC13506943

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.