ArticleFrontiers in medicine2026
Intensive vs. standard nurse-supervised blood pressure monitoring and intensive care utilization in acute hypertensive encephalopathy: a single-center retrospective cohort study.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Acute hypertensive encephalopathy (AHE), a subtype of posterior reversible encephalopathy syndrome (PRES), requires rapid blood pressure control and intensive monitoring. The 2024 American Heart Association scientific statement emphasizes the need for evidence-based approaches to inpatient blood pressure management, yet the specific role of nursing surveillance intensity in AHE outcomes remains undefined. Objective: To evaluate whether intensive nurse-supervised blood pressure monitoring reduces intensive care unit (ICU) utilization and improves clinical outcomes compared with standard care in patients with AHE. Methods: This single-center retrospective cohort study included 230 consecutive adults with AHE admitted to a district general hospital in Wuhan, China (January 2022-December 2025). Patients receiving intensive nurse-supervised monitoring (blood pressure every 15-30 min, neurological assessment every 30-60 min; Results: After matching, 97 pairs (194 patients) were analyzed and were evenly distributed across the four study years. The intensive monitoring group had a nominally lower ICU admission rate [74.2% vs. 86.6%; relative risk (RR), 0.86; 95% CI, 0.74-0.99; McNemar Conclusions: In this retrospective cohort, intensive nurse-supervised blood pressure monitoring was associated with-but not proven to cause-a lower ICU admission rate and more efficient blood pressure control, without increased adverse events. Because the primary association was statistically fragile, susceptible to confounding by indication, and not robust to multiplicity correction, these findings are hypothesis-generating and should be confirmed in a prospective randomized trial before informing practice.
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