Evidence map›Paper›PMID 42656415›Full record

ArticleFrontiers in ophthalmology2026

Preclinical evaluation of recombinant type III collagen-based contact lens rewetting drops.

Siyang Liu, Yefei Shi, Yuanxin Zhai, Jie Chen, Hanzhuang Teng, Jie Li, Yujie Meng, Jing Li, Shaohui Pan, Haihang Li and 1 more

Abstract read
In one paragraph

Article in Frontiers in ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Siyang LiuJiangsu Trautec Medical Technology Co., Ltd, Changzhou, China.
Yefei ShiAnhui Trautec Medical Technology Co., Ltd, Suzhou, China.
Yuanxin ZhaiJiangsu Trautec Medical Technology Co., Ltd, Changzhou, China.
Jie ChenJiangsu Trautec Medical Technology Co., Ltd, Changzhou, China.
Hanzhuang TengJiangsu Trautec Medical Technology Co., Ltd, Changzhou, China.
Jie LiJiangsu Trautec Medical Technology Co., Ltd, Changzhou, China.
Yujie MengJiangsu Trautec Medical Technology Co., Ltd, Changzhou, China.
Jing LiJiangsu Trautec Medical Technology Co., Ltd, Changzhou, China.
Shaohui PanEye Research Center, Hangzhou Institute of Medicine, Chinese Academy of Sciences, Eye Hospital, Wenzhou Medical University, Hangzhou, China.
Haihang LiJiangsu Trautec Medical Technology Co., Ltd, Changzhou, China.
Shuxian HuJiangsu Trautec Medical Technology Co., Ltd, Changzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate the physicochemical properties, contact lens compatibility, Methods: Physicochemical properties were characterized using rheological testing and contact angle measurements. Total residual protein on rigid gas-permeable contact lenses was evaluated using an artificial tear fluid model, followed by non-enzymatic and enzymatic cleaning procedures. Results: Col RD exhibited shear-thinning rheological behavior and a hydrophilic sequence profile, with viscosity close to that of human tears under blinking-associated shear conditions. Contact angle analysis showed no significant differences compared with commercial lubricants. In the Conclusions: Recombinant collagen-based contact lens rewetting drops showed favorable rheological properties, acceptable

Indexed as

biomaterialcontact lensrecombinant collagenrewetting dropssafetyType III collagen

Identifiers

PMID42656415
PMCPMC13506455

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.