Evidence map›Paper›PMID 42655883›Full record

ArticleScandinavian journal of primary health care2026

Barriers and motivators for opioid deprescribing among Danish adults receiving long-term treatment with short-acting opioids: an exploratory qualitative study in primary care informed by self-determination theory.

Sabrina Hoffensitz Nielsen, Line Bjørnskov Pedersen, Dorte Ejg Jarbøl, Merethe Kirstine Kousgaard Andersen, Jens Søndergaard, Carina Lundby

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Article in Scandinavian journal of primary health care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Sabrina Hoffensitz NielsenResearch Unit for General Practice, Department of Public Health, University of Southern Denmark, Odense, Denmark.ORCID 0000-0002-0677-239X
Line Bjørnskov PedersenResearch Unit for General Practice, Department of Public Health, University of Southern Denmark, Odense, Denmark.ORCID 0000-0001-6804-2045
Dorte Ejg JarbølResearch Unit for General Practice, Department of Public Health, University of Southern Denmark, Odense, Denmark.ORCID 0000-0002-3241-4190
Merethe Kirstine Kousgaard AndersenResearch Unit for General Practice, Department of Public Health, University of Southern Denmark, Odense, Denmark.ORCID 0000-0002-4833-1867
Jens SøndergaardResearch Unit for General Practice, Department of Public Health, University of Southern Denmark, Odense, Denmark.ORCID 0000-0002-1629-1864
Carina LundbyHospital Pharmacy Funen, Odense University Hospital, Odense, Denmark.ORCID 0000-0002-2121-6252

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLong-term opioid treatment for chronic non-cancer pain (CNCP) yields limited benefit and notable risk of harm. Danish guidelines discourage long-term treatment with short-acting opioids, yet short-acting opioid prescribing persists.

aimTo investigate the barriers and motivators to opioid deprescribing among adults with CNCP, receiving long-term treatment with short-acting opioids in primary care.

methodsWe conducted an explorative qualitative study using semi-structured, face-to-face interviews with adults with CNCP with long-term treatment with short-acting opioids invited through Danish primary care. The analysis was abductive inspired by reflexive thematic analysis using inductive coding and theme generation, followed by interpretation through the self-determination theory.

results11 participants were interviewed (mean age of 62 years; eight women). Three themes were generated: (1) Effects and consequences, (2) Significant relationships, and (3) The work of identity. Participants experienced that as-needed dosing with short-acting opioid provided psychological reassurance that could enable tapering engagement. In line with self-determination theory, we found that the motivational quality towards medication change varied with the degree to which the needs for: autonomy, competence, and relatedness were satisfied. Attentive and respectful care fostered identified or integrated regulation, whereas suspicion promoted controlled motivation or amotivation. Ambivalence made tapering simultaneously desirable and untenable.

conclusionsSustainable opioid reductions among adults with CNCP who use short-acting opioids long-term is not merely a technical exercise. It is inherently relational and attentive to identity. Clinical practice could beneficially address ambivalence explicitly, rather than treating it as resistance, leverage short-acting opioid flexibility as reassurance, and support autonomy, competence, and relatedness.

Indexed as

Analgesics, OpioidChronic PainDeprescriptionsMotivationPersonal AutonomyAdultAgedDenmarkFemaleHumansMaleMiddle AgedPrimary Health CareQualitative ResearchAnalgesics, OpioiddeprescribingfacilitatorsLong-term opioid treatmentmotivatorsprimary careself-determination theoryshort acting opioids

Identifiers

PMID42655883
PMCPMC13523111

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.