Evidence map›Paper›PMID 42655879›Full record

ArticleIUBMB life2026

An Ancestral Mechanism of Calmodulin Binding to Cds1 Kinase Inhibits Catalytic Activity.

Stephanie A Manovella, Tingting Wang, Samuel N Young, Toby A Dite, Vineet Vaibhav, Steve Binos, Laura F Dagley, Anh T N Nguyen, Anthony R Means, Janni Petersen and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in IUBMB life, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Stephanie A ManovellaDrug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Victoria, Australia.ORCID https://orcid.org/0009-0008-1414-9830
Tingting WangFlinders Health and Medical Research Institute, Flinders University, Adelaide, South Australia, Australia.ORCID https://orcid.org/0000-0002-7739-4787
Samuel N YoungWalter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.ORCID https://orcid.org/0009-0001-6543-1851
Toby A DiteWalter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
Vineet VaibhavWalter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
Steve BinosWalter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
Laura F DagleyWalter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.ORCID https://orcid.org/0000-0003-4171-3712
Anh T N NguyenDrug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Victoria, Australia.ORCID https://orcid.org/0000-0002-6385-0585
Anthony R MeansMolecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, USA.ORCID https://orcid.org/0000-0002-3374-6939
Janni PetersenFlinders Health and Medical Research Institute, Flinders University, Adelaide, South Australia, Australia.
John W ScottDrug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Victoria, Australia.ORCID https://orcid.org/0000-0002-1896-9798
James M MurphyDrug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Victoria, Australia.ORCID https://orcid.org/0000-0003-0195-3949
Christopher R HorneDrug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Victoria, Australia.ORCID https://orcid.org/0000-0003-1318-514X

Funding

Australian Research Council DP210102840National Health and Medical Research Council 2001817National Health and Medical Research Council 2034044National Health and Medical Research Council 2034104
6 · The paper itself

Abstract

Calmodulin is a highly conserved, calcium (Ca

Indexed as

CalmodulinCheckpoint Kinase 2SchizosaccharomycesSchizosaccharomyces pombe ProteinsCalciumCell CycleProtein BindingCalciumCalmodulinCds1 protein, S pombeCheckpoint Kinase 2Schizosaccharomyces pombe Proteins

Identifiers

PMID42655879
PMCPMC13519133

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.