Effectiveness of Non-Medical Treatment on Survival, Perioperative, and Clinical Outcomes in Canine Cushing's Syndrome: A Systematic Review and Network Meta-Analysis.

Sophia Shanlly, Jordan Slessor, Wenting Yan, Eva D C Rosaasen-Uwiera, Jessica J D Thorlakson, Heather L Bruce, Richard R E Uwiera

Abstract readReview

PubMed Full text at PMC Publisher

In one paragraph

Review in Veterinary sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sophia ShanllyDepartment of Agricultural, Food & Nutritional Science, University of Alberta, Edmonton, AB T6G 2R3, Canada.

Jordan SlessorDepartment of Mathematical & Statistical Sciences, University of Alberta, Edmonton, AB T6G 2R3, Canada.

Wenting YanFaculty of Nursing, University of Alberta, Edmonton, AB T6G 2R3, Canada.ORCID 0009-0009-2848-6659

Eva D C Rosaasen-UwieraDepartment of Psychology, University of Alberta, Edmonton, AB T6G 2R3, Canada.

Jessica J D ThorlaksonCameron Science and Engineering Library, University of Alberta, Edmonton, AB T6G 2R3, Canada.ORCID 0000-0002-2416-5024

Heather L BruceDepartment of Animal Science and Aquaculture, Dalhousie University, Truro, NS B2N 5E3, Canada.

Richard R E UwieraDepartment of Agricultural, Food & Nutritional Science, University of Alberta, Edmonton, AB T6G 2R3, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cushing's syndrome is a common endocrine disorder in dogs managed with both medical and non-medical treatments; however, the effects of non-medical interventions on survival, perioperative, and clinical outcomes remain uncertain. A comprehensive search was conducted across MEDLINE, Embase, Web of Science, Academic Search Complete, and the Cochrane Library databases. Five studies (

Indexed as

adrenalectomycanineCushing’s syndromeradiotherapysurgical treatment

Identifiers

PMID42655791

DOI10.3390/vetsci13080771

PMCPMC13517618

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.