Evidence map›Paper›PMID 42655755›Full record

ArticleVeterinary sciences2026

Exploratory Evaluation of Cardiac Fatty Acid-Binding Protein (H-FABP), Troponin I, NT-proBNP, Echocardiography, and Holter Monitoring for the Assessment of Doxorubicin-Induced Cardiac Damage in Dogs.

Paloma Nicolás-Barceló, Jesús Fortes-Díaz, Rafael Barrera, Pablo Cardenal-Morales, José Ignacio Cristóbal, Ángela Durán, Inmaculada Sevidane, Francisco Javier Duque

Abstract read
In one paragraph

Article in Veterinary sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Paloma Nicolás-BarcelóMINVET Research Group, Departamento de Medicina Animal, Facultad de Veterinaria, Universidad de Extremadura, 10003 Cáceres, Spain.
Jesús Fortes-DíazVeterinary Teaching Hospital, Veterinary Faculty, University of Extremadura, 10003 Cáceres, Spain.
Rafael BarreraMINVET Research Group, Departamento de Medicina Animal, Facultad de Veterinaria, Universidad de Extremadura, 10003 Cáceres, Spain.ORCID 0000-0003-3341-7331
Pablo Cardenal-MoralesVeterinary Teaching Hospital, Veterinary Faculty, University of Extremadura, 10003 Cáceres, Spain.ORCID 0009-0001-1033-2004
José Ignacio CristóbalMINVET Research Group, Departamento de Medicina Animal, Facultad de Veterinaria, Universidad de Extremadura, 10003 Cáceres, Spain.ORCID 0000-0001-9015-7690
Ángela DuránMINVET Research Group, Departamento de Medicina Animal, Facultad de Veterinaria, Universidad de Extremadura, 10003 Cáceres, Spain.ORCID 0000-0003-2952-0184
Inmaculada SevidaneMINVET Research Group, Departamento de Medicina Animal, Facultad de Veterinaria, Universidad de Extremadura, 10003 Cáceres, Spain.
Francisco Javier DuqueMINVET Research Group, Departamento de Medicina Animal, Facultad de Veterinaria, Universidad de Extremadura, 10003 Cáceres, Spain.ORCID 0000-0003-3110-6062

Funding

Government of Extremadura GR24094
6 · The paper itself

Abstract

Doxorubicin-induced cardiotoxicity is an important concern in veterinary oncology, and early detection of myocardial injury remains clinically challenging. This exploratory pilot study described changes in cardiac fatty acid-binding protein (h-FABP), cardiac troponin I (cTnI), NT-proBNP, conventional echocardiographic variables, and 24-h Holter-derived heart rate variability parameters in dogs with hemangiosarcoma treated with doxorubicin. Fourteen dogs were prospectively evaluated before treatment initiation and one week after the third doxorubicin dose, corresponding to a cumulative dose of 90 mg/m

Indexed as

caninescardiotoxicitydoxorubicinh-FABPHoltertroponin I

Identifiers

PMID42655755
PMCPMC13517254

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.