Evidence map›Paper›PMID 42655704›Full record

ArticleViruses2026

Impact of SARS-CoV-2 Pandemic on Neuroinfectious Etiology in the Lazio Region: Evidence from Laboratory-Based Surveillance Analysis.

Martina Rueca, Sara Leone, Maria Beatrice Valli, Gabriella De Carli, Gaetano Maffongelli, Eleonora Lalle, Federica Forbici, Maria Concetta Fusco, Alessandra Amendola, Lavinia Fabeni and 6 more

Abstract read
In one paragraph

Article in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Martina RuecaLaboratory of Virology and Laboratories of Biosecurity, National Institute for Infectious Diseases 'Lazzaro Spallanzani'-IRCCS, 00149 Rome, Italy.ORCID 0000-0001-5162-046X
Sara LeoneClinical Epidemiology and Biostatistics Unit, Department of Epidemiology, Preclinical Research and Advanced Diagnostic, National Institute for Infectious Diseases 'Lazzaro Spallanzani'-IRCCS, 00149 Rome, Italy.ORCID 0009-0006-3723-0127
Maria Beatrice ValliLaboratory of Virology and Laboratories of Biosecurity, National Institute for Infectious Diseases 'Lazzaro Spallanzani'-IRCCS, 00149 Rome, Italy.ORCID 0000-0001-5022-5388
Gabriella De CarliRegional Service for Surveillance and Control of Infectious Diseases (SERESMI), National Institute for Infectious Diseases 'Lazzaro Spallanzani'-IRCCS, 00149 Rome, Italy.ORCID 0000-0002-3972-8301
Gaetano MaffongelliClinical Department, National Institute for Infectious Diseases 'Lazzaro Spallanzani'-IRCCS, 00149 Rome, Italy.ORCID 0000-0001-7784-2511
Eleonora LalleLaboratory of Virology and Laboratories of Biosecurity, National Institute for Infectious Diseases 'Lazzaro Spallanzani'-IRCCS, 00149 Rome, Italy.
Federica ForbiciLaboratory of Virology and Laboratories of Biosecurity, National Institute for Infectious Diseases 'Lazzaro Spallanzani'-IRCCS, 00149 Rome, Italy.ORCID 0000-0002-3954-5679
Maria Concetta FuscoRegional Service for Surveillance and Control of Infectious Diseases (SERESMI), National Institute for Infectious Diseases 'Lazzaro Spallanzani'-IRCCS, 00149 Rome, Italy.
Alessandra AmendolaLaboratory of Virology and Laboratories of Biosecurity, National Institute for Infectious Diseases 'Lazzaro Spallanzani'-IRCCS, 00149 Rome, Italy.ORCID 0000-0002-7063-0222
Lavinia FabeniLaboratory of Virology and Laboratories of Biosecurity, National Institute for Infectious Diseases 'Lazzaro Spallanzani'-IRCCS, 00149 Rome, Italy.ORCID 0000-0002-2975-8611
Maria Letizia GiancolaClinical Department, National Institute for Infectious Diseases 'Lazzaro Spallanzani'-IRCCS, 00149 Rome, Italy.
Alessandro AgrestaRegional Service for Surveillance and Control of Infectious Diseases (SERESMI), National Institute for Infectious Diseases 'Lazzaro Spallanzani'-IRCCS, 00149 Rome, Italy.ORCID 0000-0001-8890-0342
Tommaso Ascoli BartoliClinical Department, National Institute for Infectious Diseases 'Lazzaro Spallanzani'-IRCCS, 00149 Rome, Italy.
Emanuele NicastriClinical Department, National Institute for Infectious Diseases 'Lazzaro Spallanzani'-IRCCS, 00149 Rome, Italy.ORCID 0000-0002-5606-8712
Fabrizio MaggiLaboratory of Virology and Laboratories of Biosecurity, National Institute for Infectious Diseases 'Lazzaro Spallanzani'-IRCCS, 00149 Rome, Italy.ORCID 0000-0001-7489-5271
Francesco VairoRegional Service for Surveillance and Control of Infectious Diseases (SERESMI), National Institute for Infectious Diseases 'Lazzaro Spallanzani'-IRCCS, 00149 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mitigation measures adopted to reduce the spread of COVID-19 have not only impacted the transmission of respiratory infections but also other infectious diseases. In this study, we explored the effect of the pandemic on the epidemiology of Central Nervous System (CNS) infections by conducting a retrospective analysis of diagnostic data obtained from cerebrospinal fluids (CSFs) collected before, during, and after the pandemic from patients with acute-suspected neuro-infectious syndrome. The samples were analyzed using a meningitis/encephalitis molecular syndromic panel. A total of 4203 CSFs were split into three groups: pre-pandemic (August 2018-February 2020), pandemic (March 2020-March 2022) and post-pandemic (April 2022-March 2024). Each pathogen was statistically assessed individually, comparing one group vs. another. Results showed that viral pathogens were the most frequently detected across all groups; however,

Indexed as

Central Nervous System InfectionsCOVID-19HumansItalyPandemicsRetrospective StudiesSARS-CoV-2enterovirusmeningo-encephalitismolecular diagnosticsSARS-CoV-2

Identifiers

PMID42655704
PMCPMC13517623

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.