Evidence map›Paper›PMID 42655648›Full record

ArticleViruses2026

Oropouche Virus: Comparative Study of Two Strains Reveals Distinct Innate Immunity Modulation.

Letizia Rizzo, Giulia Alessandri, Gianni Gori Savellini, Sara Caldrer, Concetta Castilletti, Maria Grazia Cusi

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Letizia RizzoDepartment of Medical Biotechnologies, University of Siena, Viale Bracci 16, 53100 Siena, Italy.
Giulia AlessandriDepartment of Medical Biotechnologies, University of Siena, Viale Bracci 16, 53100 Siena, Italy.
Gianni Gori SavelliniDepartment of Medical Biotechnologies, University of Siena, Viale Bracci 16, 53100 Siena, Italy.ORCID 0000-0003-2287-9258
Sara CaldrerVirology and Emerging Pathogens Unit, Department of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, 37024 Verona, Italy.ORCID 0000-0002-2379-1082
Concetta CastillettiVirology and Emerging Pathogens Unit, Department of Infectious, Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, 37024 Verona, Italy.ORCID 0000-0001-9819-236X
Maria Grazia CusiDepartment of Medical Biotechnologies, University of Siena, Viale Bracci 16, 53100 Siena, Italy.ORCID 0000-0001-8869-8164

Funding

Ministero dell'università e della ricerca NextGeneration EU-MUR PNRR Extended Partnership initiative on Emerging Infectious Diseases INF-ACT Grant No. PE00000007
6 · The paper itself

Abstract

Oropouche virus (OROV), an Orthobunyavirus of the

Indexed as

Bunyaviridae InfectionsImmunity, InnateOrthobunyavirusViral Nonstructural ProteinsAnimalsCell LineDEAD Box Protein 58HumansInterferon-betaInterferon Regulatory Factor-3Promoter Regions, GeneticReceptors, ImmunologicSignal TransductionDEAD Box Protein 58Interferon-betaInterferon Regulatory Factor-3IRF3 protein, humanReceptors, ImmunologicRIGI protein, humanViral Nonstructural Proteinsinterferon betanon-structural NSs proteinOropouche virusRPB1 subunit proteinvirus fitness

Identifiers

PMID42655648
PMCPMC13517354

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.