Graphene-Based Sensors for Food Freshness Monitoring: Recent Advances, Performance, and Practical Challenges.

Food spoilage along the supply chain represents a major global challenge, contributing to economic losses, environmental impacts, and food safety concerns. Graphene-based materials have emerged as promising platforms for real-time food freshness monitoring owing to their high surface area, electrical conductivity, chemical sensitivity, and compatibility with flexible sensing architectures. This review critically examines graphene-based sensing strategies for food freshness and spoilage monitoring, including chemiresistive, dielectric, field-effect, optical/fluorescence, photoelectrochemical, mass-sensitive, and colorimetric approaches. Representative sensing platforms are compared in terms of analytical performance, including detection range, limit of detection, selectivity, response and recovery times, calibration, reproducibility, and stability. Particular attention is given to machine-learning-assisted sensing, multifunctional platforms for temperature, humidity, and gas monitoring, and the challenges associated with real-world implementation, including environmental interference, sensor fouling, signal drift, long-term stability, and cross-matrix validation. Finally, commercialization readiness, integration into intelligent packaging, and safety and regulatory considerations related to graphene-based food-contact applications are discussed. Overall, the review identifies the main technological gaps and future research priorities toward robust, scalable, and practical graphene-based systems for real-time food freshness monitoring.