ArticleSensors (Basel, Switzerland)2026
Instrumented Timed Up and Go Analysis Identifies Biomechanical Markers Across Early Hoehn and Yahr Stages of Parkinson's Disease.
Paula Molero-Mateo, Carlota Trigo, Adriana Torres-Pardo, Diego Fernández-Vázquez, Diego Torricelli, İrem Akgün, Jorge Andrés Gómez-García, Marina Algaba-Vidoy, María Carratalá-Tejada, Simón García-Diego-Martínez and 4 more
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In one paragraphArticle in Sensors (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
14 authors.
Paula Molero-MateoEscuela Internacional de Doctorado, Rey Juan Carlos University, 28933 Móstoles, Spain.ORCID 0009-0006-6754-9286 Carlota TrigoBioRobotics Group, Centre for Automation and Robotics (CAR), Spanish National Research Council, 28006 Arganda del Rey, Spain.ORCID 0009-0001-5535-0951 Adriana Torres-PardoBioRobotics Group, Centre for Automation and Robotics (CAR), Spanish National Research Council, 28006 Arganda del Rey, Spain.ORCID 0000-0001-9095-6927 Diego Fernández-VázquezLaboratory of Movement Analysis, Biomechanics, Ergonomics and Motor Control (LAMBECOM), Faculty of Health Sciences, Rey Juan Carlos University, 28922 Alcorcón, Spain.ORCID 0000-0002-7766-1507 Diego TorricelliBioRobotics Group, Centre for Automation and Robotics (CAR), Spanish National Research Council, 28006 Arganda del Rey, Spain.ORCID 0000-0001-8767-3395 İrem AkgünDepartment of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Gaziantep University, 27410 Gaziantep, Türkiye.
Jorge Andrés Gómez-GarcíaBioRobotics Group, Centre for Automation and Robotics (CAR), Spanish National Research Council, 28006 Arganda del Rey, Spain.ORCID 0000-0002-6060-387X Marina Algaba-VidoyBioRobotics Group, Centre for Automation and Robotics (CAR), Spanish National Research Council, 28006 Arganda del Rey, Spain.ORCID 0000-0001-6362-3748 María Carratalá-TejadaLaboratory of Movement Analysis, Biomechanics, Ergonomics and Motor Control (LAMBECOM), Faculty of Health Sciences, Rey Juan Carlos University, 28922 Alcorcón, Spain.ORCID 0000-0003-2825-8655 Simón García-Diego-MartínezEscuela Internacional de Doctorado, Rey Juan Carlos University, 28933 Móstoles, Spain.ORCID 0009-0009-3250-5410 Víctor Navarro-LópezLaboratory of Movement Analysis, Biomechanics, Ergonomics and Motor Control (LAMBECOM), Faculty of Health Sciences, Rey Juan Carlos University, 28922 Alcorcón, Spain.ORCID 0000-0003-1362-6312 Yeray González-ZamoranoDepartment of Physical Therapy, Occupational Therapy, Physical Medicine, and Rehabilitation, Faculty of Health Sciences, Rey Juan Carlos University, 28922 Alcorcón, Spain.
Isabel Mª Alguacil-DiegoLaboratory of Movement Analysis, Biomechanics, Ergonomics and Motor Control (LAMBECOM), Faculty of Health Sciences, Rey Juan Carlos University, 28922 Alcorcón, Spain.ORCID 0000-0002-2054-3622 Francisco Molina-RuedaLaboratory of Movement Analysis, Biomechanics, Ergonomics and Motor Control (LAMBECOM), Faculty of Health Sciences, Rey Juan Carlos University, 28922 Alcorcón, Spain.ORCID 0000-0002-8616-5505 Funding
Spanish Ministry of Science and Innovation (MCIN) MCIN/AEI/10.13039/501100011033the European Union (FEDER) PID2024-162745OB-I00
6 · The paper itselfAbstract
The Timed Up and Go (TUG) test is widely used to assess functional mobility in Parkinson's disease (PD), although total test duration may overlook phase-specific biomechanical alterations. This cross-sectional study investigated whether phase-specific analysis of the instrumented TUG (iTUG) could identify candidate biomechanical markers characterizing differences among early-stage PD subgroups and healthy controls. Seventy-nine participants (38 PD, 41 controls) performed four iTUG trials in the OFF-medication state. Movement data were collected using synchronized inertial measurement units and optoelectronic motion capture systems. The iTUG was segmented into six phases, and temporal, spatiotemporal, variability, and multisegmental kinematic parameters were analyzed. Participants with PD at modified Hoehn and Yahr (mH&Y) stage 2 performed the iTUG more slowly than controls (
Indexed as
Parkinson DiseaseAgedBiomechanical PhenomenaCross-Sectional StudiesFemaleGaitHumansMaleMiddle AgedMotion CaptureMovementWalkingbiomechanical markersgait analysisInstrumented Timed Up and Gomotion capturemotor controlParkinson’s diseasewearable sensors
Identifiers
PMID42655485
PMCPMC13517892
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