Vaginal

Xu Han, Baiyun Sun, Yan Zhu, Yanan Liu

Abstract read

In one paragraph

Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xu HanDepartment of Obstetrics and Gynecology, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.

Baiyun SunDepartment of Obstetrics and Gynecology, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.

Yan ZhuDepartment of Obstetrics and Gynecology, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.

Yanan LiuDepartment of Obstetrics and Gynecology, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genitourinary syndrome of menopause (GSM) is a common chronic condition in postmenopausal women, yet biomarkers predicting response to local estrogen therapy remain insufficiently defined. In this prospective study, 216 postmenopausal women with GSM received local estradiol vaginal tablet therapy for 12 weeks. Baseline assessments included symptom evaluation, vaginal pH, vaginal maturation index (VMI), and quantitative real-time PCR measurement of six target microorganisms. Treatment response was defined as an improvement of at least 2 points in the most bothersome symptom (MBS) score. After 12 weeks, MBS score, vaginal pH, and VMI improved significantly, with increased abundance of

Indexed as

genitourinary syndrome of menopauseLactobacillus inerslocal estrogen therapytreatment responsevaginal microbiota

Identifiers

PMID42655105

DOI10.3390/microorganisms14081760

PMCPMC13515633

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.