Evidence map›Paper›PMID 42655095›Full record

ArticleMicroorganisms2026

Clinical Evaluation of a Tandem qPCR-CRISPR Assay for Multidrug-Resistant or Rifampicin-Resistant Tuberculosis: A Prospective Diagnostic Accuracy Study.

Ying Wang, Zhe Song, Jianfeng Zeng, Yajuan Dong, Houming Liu, Jian Zeng, Xuhui Liu, Liang Fu, Xuelin Li, Shuihua Lu and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ying WangShanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai 200032, China.
Zhe SongNational Clinical Research Center for Infectious Disease, Shenzhen 518112, China.
Jianfeng ZengNational Clinical Research Center for Infectious Disease, Shenzhen 518112, China.
Yajuan DongShanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai 200032, China.
Houming LiuDepartment of Clinical Laboratory, Shenzhen Third People's Hospital, Shenzhen 518112, China.
Jian ZengNational Clinical Research Center for Infectious Disease, Shenzhen 518112, China.
Xuhui LiuShanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai 200032, China.
Liang FuNational Clinical Research Center for Infectious Disease, Shenzhen 518112, China.
Xuelin LiNational Clinical Research Center for Infectious Disease, Shenzhen 518112, China.
Shuihua LuNational Clinical Research Center for Infectious Disease, Shenzhen 518112, China.
Zhen HuangNational Clinical Research Center for Infectious Disease, Shenzhen 518112, China.
Xiao-Yong FanShanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai 200032, China.ORCID 0000-0001-6654-3559

Funding

Guangdong Basic and Applied Basic Research Foundation 2025A1515011871National Natural Science Foundation of China 82302614Shanghai Municipal Science and Technology Major Project ZD2021CY001Shenzhen Medical Academy of Research and Translation D250403009Shenzhen Science and Technology Program JSGGZD20220822095200001
6 · The paper itself

Abstract

CRISPR-based assays have shown the potential to enhance the diagnosis of tuberculosis (TB), but evidence remains limited owing to scarce independent validation. We prospectively evaluated a tandem qPCR-CRISPR assay detecting

Indexed as

CRISPRdiagnosticsdrug resistancetuberculosis

Identifiers

PMID42655095
PMCPMC13515032

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.