ReviewMicroorganisms2026
Next-Generation Probiotics in Poultry: From Conventional Strains to Engineered and Synbiotic Approaches.
Review in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The global poultry industry faces a major transition driven by bans on antibiotic growth promoters (AGPs) and rising antimicrobial resistance threats. This has intensified the search for effective, sustainable alternatives to maintain productivity, animal health, and food safety. This review provides a comprehensive overview of next-generation probiotics (NGPs) and their evolving role in poultry production, highlighting their mechanisms of action, technological advancements, and applications for improving performance and health. Recent studies were systematically reviewed, covering conventional and NGPs, multi-omics-driven strain identification strategies, engineered microbial systems, and advanced delivery technologies. Key functional aspects, including gut microbiota modulation, immune responses, pathogen control, and productivity metrics were thoroughly assessed. NGPs exhibit enhanced capabilities over traditional probiotics, including improved gut colonization, targeted antimicrobial activity, and precise host immune modulation. Advances in synthetic biology, microencapsulation, and synbiotic formulations enhance their efficacy and stability. Additionally, NGPs also demonstrate significant potential in improving growth performance, feed conversion ratios, intestinal integrity, and enteric pathogen resistance. However, challenges such as strain-specific variability, regulatory constraints, and limited field-level validation persist. NGPs offer a promising and sustainable strategy for modern poultry production. Future integration with precision microbiome engineering, artificial intelligence, and sustainable farming will be essential to realize their full potential and ensure widespread adoption.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.