Evidence map›Paper›PMID 42654760›Full record

ArticlePathogens (Basel, Switzerland)2026

In Vitro and In Vivo Antiviral Activity of a Modified Medium-Chain Fatty Acid Against Porcine Reproductive and Respiratory Syndrome Virus.

Nader Maher Sobhy, Valeria Lugo-Mesa, Christiana Rezk Bottros Youssef, Cecilia Balestreri, Yuan-Tai Hung, Gary D Reznik, Declan C Schroeder, Sagar Mal Goyal

Abstract read
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In one paragraph

Article in Pathogens (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nader Maher SobhyDepartment of Veterinary Population Medicine, University of Minnesota, St. Paul, MN 55108, USA.
Valeria Lugo-MesaDepartment of Veterinary Population Medicine, University of Minnesota, St. Paul, MN 55108, USA.ORCID 0009-0003-0110-950X
Christiana Rezk Bottros YoussefDepartment of Veterinary Population Medicine, University of Minnesota, St. Paul, MN 55108, USA.
Cecilia BalestreriDepartment of Veterinary Population Medicine, University of Minnesota, St. Paul, MN 55108, USA.ORCID 0000-0002-8855-7772
Yuan-Tai HungDevenish Nutrition LLC, 2320 Lake Ave., Fairmont, MN 56031, USA.
Gary D ReznikDevenish Nutrition LLC, 2320 Lake Ave., Fairmont, MN 56031, USA.
Declan C SchroederDepartment of Veterinary Population Medicine, University of Minnesota, St. Paul, MN 55108, USA.ORCID 0000-0001-5991-2838
Sagar Mal GoyalDepartment of Veterinary Population Medicine, University of Minnesota, St. Paul, MN 55108, USA.ORCID 0000-0002-7781-3080

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porcine reproductive and respiratory syndrome virus (PRRSV) causes significant economic losses in the global swine industry, partly because current vaccination strategies offer limited protection against heterologous viral strains. Since modified medium-chain fatty acids (mMCFA) offer enhanced structural stability and antimicrobial properties compared with unmodified MCFA, we evaluated a proprietary mMCFA blend (D-Strike, Devenish Nutrition) against PRRSV in vitro and in vivo. In vitro efficacy was assessed using TCID

Indexed as

Antiviral AgentsFatty AcidsPorcine Reproductive and Respiratory SyndromePorcine respiratory and reproductive syndrome virusAnimal FeedAnimalsCell LineChlorocebus aethiopsLactatesRandom AllocationRNA, ViralSwineAntiviral AgentsFatty AcidsLactatesRNA, ViralD-Strikefeed efficiencymMCFApigsPRRSVviability RT-PCR

Identifiers

PMID42654760
PMCPMC13516076

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.