Evidence map›Paper›PMID 42654502›Full record

SynthesisMedicina (Kaunas, Lithuania)2026

Renal Safety of Topical Diclofenac in Adults with Increased Renal Risk: A Systematic Review.

Eric-Oliviu Coșovanu, Elena-Teona Coșovanu, Teodora Ana Balan, Cezar Ilie Foia, Cosmin Gabriel Tarțău, Tiberiu Lunguleac, Aurelian-Bogdan Stana, Antoneta Dacia Petroaie, Simona Eliza Giușcă, Elena Adorata Coman and 5 more

Abstract readSystematic ReviewReview
In one paragraph

Synthesis in Medicina (Kaunas, Lithuania), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Eric-Oliviu Coșovanu"Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania.ORCID 0009-0005-1766-8060
Elena-Teona Coșovanu"Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania.ORCID 0009-0005-5166-1970
Teodora Ana Balan"Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania.ORCID 0009-0008-9036-1534
Cezar Ilie Foia"Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania.ORCID 0009-0001-9989-1653
Cosmin Gabriel Tarțău"Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania.ORCID 0000-0002-2343-5782
Tiberiu Lunguleac"Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania.ORCID 0009-0003-2268-0000
Aurelian-Bogdan Stana"Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania.
Antoneta Dacia Petroaie"Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania.ORCID 0000-0002-1239-8058
Simona Eliza Giușcă"Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania.ORCID 0000-0002-6321-7253
Elena Adorata Coman"Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania.ORCID 0000-0002-6348-2954
Demetra Socolov"Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania.ORCID 0000-0002-0979-0200
Raluca Anca Balan"Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania.ORCID 0000-0003-2875-8991
Ramona Gabriela Ursu"Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania.ORCID 0000-0002-1811-7923
Irina-Draga Căruntu"Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania.ORCID 0000-0002-0104-8503
Liliana Mititelu-Tarțău"Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania.ORCID 0000-0001-7983-3811

Funding

The Health Programme (PS) 2021-2027 INNODOC-MED, SMIS code 351058
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Inflammatory Agents, Non-SteroidalDiclofenacKidneyAdministration, TopicalAdultHumansOsteoarthritisAnti-Inflammatory Agents, Non-SteroidalDiclofenacacute kidney injurychronic kidney diseasedrug safetyGRADEnon-steroidal anti-inflammatory drugsosteoarthritispharmacovigilancerenal safetysystematic reviewtopical diclofenac

Identifiers

PMID42654502
PMCPMC13515200

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.