ArticlePharmaceutics2026
Engineering Allogeneic FE002-Cart Chondroprogenitor Spheroids for Large Knee Chondral Defects: Investigating Microenvironmental Cues for Functional Control, GMP Formulation, and Logistical Viability.
Lee Ann Applegate, Farid Hadjab, Sandra Jaccoud, Alexandre Porcello, Virginie Philippe, Nathalie Hirt-Burri, Corinne Scaletta, Brigitte M Jolles, Dominique P Pioletti, Robin Martin and 1 more
Abstract read
In one paragraphArticle in Pharmaceutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
11 authors.
Lee Ann ApplegateRegenerative Therapy Unit, Lausanne University Hospital, University of Lausanne, CH-1066 Epalinges, Switzerland.ORCID 0000-0002-7346-9921 Farid HadjabDevelopment Department, Albomed GmbH, D-90592 Schwarzenbruck, Germany.
Sandra JaccoudRegenerative Therapy Unit, Lausanne University Hospital, University of Lausanne, CH-1066 Epalinges, Switzerland.
Alexandre PorcelloDevelopment Department, LOUNA REGENERATIVE SA, CH-1228 Plan-les-Ouates, Switzerland.ORCID 0000-0003-1603-2704 Virginie PhilippeRegenerative Therapy Unit, Lausanne University Hospital, University of Lausanne, CH-1066 Epalinges, Switzerland.ORCID 0000-0003-3544-0383 Nathalie Hirt-BurriRegenerative Therapy Unit, Lausanne University Hospital, University of Lausanne, CH-1066 Epalinges, Switzerland.ORCID 0000-0003-1220-0213 Corinne ScalettaRegenerative Therapy Unit, Lausanne University Hospital, University of Lausanne, CH-1066 Epalinges, Switzerland.ORCID 0000-0002-7682-9160 Brigitte M JollesDepartment of Musculoskeletal Medicine, Swiss BioMotion Lab, Lausanne University Hospital and University of Lausanne (CHUV-UNIL), CH-1011 Lausanne, Switzerland.
Dominique P PiolettiLaboratory of Biomechanical Orthopedics, Federal Polytechnic School of Lausanne, CH-1015 Lausanne, Switzerland.ORCID 0000-0001-5535-5296 Robin MartinOrthopedic Surgery Service, Fribourg Hospital, CH-1752 Villars-sur-Glâne, Switzerland.
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
PubMed holds no abstract for this paper.
Indexed as
advanced therapy medicinal products (ATMP)allogeneic cytotherapiescartilage tissue engineeringcell formulationchondrogenesisgood manufacturing practice (GMP)hypoxiamanufacturing processoff-the-shelf implantsthree-dimensional spheroids
Identifiers
PMID42654149
PMCPMC13516314
What OpenQuestion holds
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