Evidence map›Paper›PMID 42653923›Full record

ArticleMolecules (Basel, Switzerland)2026

Unexpected Synthesis of a Furoxan Derivative from 3-Acetyl-2,4,6-Trimethylpyridine: Structural Characterization and Biological Evaluation.

Aida S Rakhimzhanova, Irina A Pustolaikina, Alfiya F Kurmanova, Ruslan A Muzaparov, Tatyana V Rybalova, Zarina T Shulgau, Alena L Stalinskaya, Ivan V Kulakov

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aida S RakhimzhanovaDepartment of Physical and Analytical Chemistry, Buketov Karaganda National Research University, Karaganda 100024, Kazakhstan.ORCID 0000-0002-4984-623X
Irina A PustolaikinaDepartment of Physical and Analytical Chemistry, Buketov Karaganda National Research University, Karaganda 100024, Kazakhstan.ORCID 0000-0001-6319-666X
Alfiya F KurmanovaDepartment of Physical and Analytical Chemistry, Buketov Karaganda National Research University, Karaganda 100024, Kazakhstan.
Ruslan A MuzaparovDepartment of Physical and Analytical Chemistry, Buketov Karaganda National Research University, Karaganda 100024, Kazakhstan.ORCID 0009-0005-4480-4355
Tatyana V RybalovaN. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of the Siberian Branch of Russian Academy of Sciences, Novosibirsk 630090, Russia.ORCID 0000-0003-2398-5271
Zarina T ShulgauDepartment of Science Development, Astana Medical University, Astana 010000, Kazakhstan.ORCID 0000-0001-8148-0816
Alena L StalinskayaHigher School of Natural Science, University of Tyumen, Tyumen 625003, Russia.ORCID 0000-0002-2172-074X
Ivan V KulakovDepartment of Physical and Analytical Chemistry, Buketov Karaganda National Research University, Karaganda 100024, Kazakhstan.ORCID 0000-0001-5772-2096

Funding

Science Committee of the Ministry of Science and Higher Education of the Republic of Kazakhstan AP23488790
6 · The paper itself

Abstract

Herein, we report an unexpected pseudo-multicomponent transformation discovered during attempts to selectively nitrate the pyridine core of 3-acetyl-2,4,6-trimethylpyridine (

Indexed as

OxadiazolesPyridinesCrystallography, X-RayModels, MolecularMolecular StructurefuroxansOxadiazolesPyridines1,2,5-oxadiazole 2-oxides1,2,5-oxadiazoles3-acetyl-2,4,6-trimethylpyridineacetylpyridinescrystal structurecyclizationDFT calculationsfuroxanshemorheological activityMMP-9molecular dockingnitrationperturbation theorypseudo-multicomponent reactionspyridine derivatives

Identifiers

PMID42653923
PMCPMC13515417

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.