ArticleMolecules (Basel, Switzerland)2026
Identification and Structure-Activity Relationship of a Novel Dermatoxin-like Antimicrobial Peptide with Partial LPS-Mediated Membrane Interaction.
Shiya Cheng, Yu Zai, Jiayi Peng, Jie Xiang, Xiaoling Chen, Chengbang Ma, Yangyang Jiang, Tao Wang, Tianbao Chen, Chris Shaw and 2 more
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In one paragraphArticle in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
12 authors.
Shiya ChengNatural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK.
Yu ZaiNatural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK.
Jiayi PengNatural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK.
Jie XiangNatural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK.ORCID 0000-0002-3107-9888 Xiaoling ChenNatural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK.
Chengbang MaNatural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK.
Yangyang JiangNatural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK.ORCID 0000-0002-5349-8354 Tao WangNatural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK.ORCID 0000-0003-3111-2024 Tianbao ChenNatural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK.ORCID 0000-0001-8011-9260 Chris ShawNatural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK.
Mei ZhouNatural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK.ORCID 0000-0003-2576-0252 Lei WangNatural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK.ORCID 0000-0002-8811-8489 Funding
General Project of Natural Science Research in Jiangsu Province 22KJB180011Jiangsu Province Double Innovation Doctoral Program JSSCBS20220478
6 · The paper itselfAbstract
The rapid emergence of antimicrobial resistance necessitates the development of novel antimicrobial agents with improved efficacy and selectivity. In this study, a dermatoxin-like peptide, dermatoxin-PD1, was identified from the skin secretion of
Indexed as
Antimicrobial Cationic PeptidesAntimicrobial PeptidesCell MembraneLipopolysaccharidesAmino Acid SequenceAnimalsGram-Negative BacteriaHumansMicrobial Sensitivity TestsStructure-Activity RelationshipAntimicrobial Cationic PeptidesAntimicrobial PeptidesLipopolysaccharidesantimicrobial peptidesdermatoxinlipopolysaccharide interactionpeptide truncationstructure–activity relationship
Identifiers
PMID42653830
PMCPMC13515218
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