Evidence map›Paper›PMID 42653800›Full record

ArticlePharmaceuticals (Basel, Switzerland)2026

BioFRAM PGx, an Implementation Proposal for Pharmacogenetics in the Spanish National Health System.

Francisco Arias-Aragón, Carmen Mata-Martín, Alba Sánchez-Redondo, Jesús Novalbos, Miguel Ángel Seguido, Francisco Abad-Santos, Mar Hernaez, Mercè Brunet, David Hansoe Heredero-Jung, Alejandro de la Sota-Pérez and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Francisco Arias-AragónInstituto Universitario de Investigación Biosanitaria de Extremadura (INUBE), 06080 Badajoz, Spain.ORCID 0000-0002-6394-0193
Carmen Mata-MartínInstituto Universitario de Investigación Biosanitaria de Extremadura (INUBE), 06080 Badajoz, Spain.ORCID 0000-0002-1849-1093
Alba Sánchez-RedondoInstituto Universitario de Investigación Biosanitaria de Extremadura (INUBE), 06080 Badajoz, Spain.
Jesús NovalbosClinical Pharmacology Department, Hospital Universitario de La Princesa, Pharmacology Department, Faculty of Medicine, Instituto de Investigación Sanitaria la Princesa (IIS-Princesa), Universidad Autónoma de Madrid, 28006 Madrid, Spain.ORCID 0000-0001-5384-4512
Miguel Ángel SeguidoClinical Pharmacology Department, Hospital Universitario de La Princesa, Pharmacology Department, Faculty of Medicine, Instituto de Investigación Sanitaria la Princesa (IIS-Princesa), Universidad Autónoma de Madrid, 28006 Madrid, Spain.
Francisco Abad-SantosClinical Pharmacology Department, Hospital Universitario de La Princesa, Pharmacology Department, Faculty of Medicine, Instituto de Investigación Sanitaria la Princesa (IIS-Princesa), Universidad Autónoma de Madrid, 28006 Madrid, Spain.ORCID 0000-0002-6519-8885
Mar HernaezPharmacology and Toxicology Laboratory, Biochemistry and Molecular Genetics Department, Biomedical Diagnostic Center, Hospital Clinic of Barcelona, University of Barcelona, Fundació Clínic per a la Recerca Biomèdica (FCRB), 08036 Barcelona, Spain.ORCID 0009-0003-5352-3462
Mercè BrunetPharmacology and Toxicology Laboratory, Biochemistry and Molecular Genetics Department, Biomedical Diagnostic Center, Hospital Clinic of Barcelona, University of Barcelona, Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FCRB-IDIBAPS), Centro de Investigación Biomédica en Red Enfermedades Hepáticas y Digestivas (CIBERehd), 08036 Barcelona, Spain.
David Hansoe Heredero-JungInstitute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain.ORCID 0000-0002-6631-9319
Alejandro de la Sota-PérezInstitute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain.
María Isidoro-GarcíaInstitute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain.
Almudena Gil-RodriguezPharmacogenomics and Drug Discovery Group (GenDeM), Health Research Institute of Santiago de Compostela (IDIS), 15706 Santiago de Compostela, Spain.ORCID 0000-0002-7637-6915
Alba Barral-RañaPharmacogenomics and Drug Discovery Group (GenDeM), Health Research Institute of Santiago de Compostela (IDIS), 15706 Santiago de Compostela, Spain.
Olalla MaroñasPharmacogenomics and Drug Discovery Group (GenDeM), Health Research Institute of Santiago de Compostela (IDIS), 15706 Santiago de Compostela, Spain.
Gladys Guadalupe Olivera PasquiniDepartment of Pharmacology, Universitat de València, 46100 Valencia, Spain.
Enrique G ZucchetDepartment of Pharmacology, Universitat de València, 46100 Valencia, Spain.ORCID 0009-0003-2542-1776
María José HerreroDepartment of Pharmacology, Universitat de València, 46100 Valencia, Spain.ORCID 0000-0002-6042-4185
José Manuel Dodero-AnilloClinical Pharmacology Unit, Hospital Universitario de Puerto Real, 11510 Puerto Real, Spain.ORCID 0000-0001-9731-6105
Alicia Alba MáñezClinical Pharmacology Unit, Hospital Universitario de Puerto Real, 11510 Puerto Real, Spain.
María José Pedrosa-MartínezClinical Pharmacology Unit, Hospital Universitario de Puerto Real, 11510 Puerto Real, Spain.
Adrián LlerenaInstituto Universitario de Investigación Biosanitaria de Extremadura (INUBE), 06080 Badajoz, Spain.
On Behalf Of The BioFRAM PGx Consortium

Funding

Institute of Health Carlos III PMP22/00099, PMP22/00056, PMP22/00124, PMP22/00139, PMP22/00134
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

adverse drug reactionsclinical guidelineslevel 1a evidencemulticentre studypersonalized medicinepharmacogeneticspharmacogenomics implementationSpanish National Health System

Identifiers

PMID42653800
PMCPMC13516022

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.