Evidence map›Paper›PMID 42653764›Full record

ReviewPharmaceuticals (Basel, Switzerland)2026

Pyrroloquinoline Quinone and NAD

Alessandro Medoro, Sergio Davinelli, Cosimo Giuseppe Mazzotta, Luca Agnifili, Giovanni Scapagnini

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alessandro MedoroDepartment of Medicine and Health Sciences "V. Tiberio", Università degli Studi del Molise, 86100 Campobasso, Italy.ORCID 0000-0002-6285-607X
Sergio DavinelliDepartment of Medicine and Health Sciences "V. Tiberio", Università degli Studi del Molise, 86100 Campobasso, Italy.ORCID 0000-0003-2578-7199
Cosimo Giuseppe MazzottaDepartment of Medicine and Surgery, Ophthalmology Unit, Faculty of Medicine and Surgery, University Kore of Enna, 94100 Enna, Italy.ORCID 0000-0002-1829-9288
Luca AgnifiliOphthalmology Clinic, Department of Medicine and Ageing Science, University "G. d'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-1625-6305
Giovanni ScapagniniDepartment of Medicine and Health Sciences "V. Tiberio", Università degli Studi del Molise, 86100 Campobasso, Italy.ORCID 0000-0003-1592-5586

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glaucoma is the leading cause of irreversible blindness worldwide and a paradigmatic age-related neurodegenerative disease in which retinal ganglion cells (RGCs) are selectively lost through mechanisms that extend beyond intraocular pressure. Age-dependent NAD

Indexed as

age-related diseaseagingglaucomaNAD+ metabolismneuroprotectionpyrroloquinoline quinoneretinal ganglion cell

Identifiers

PMID42653764
PMCPMC13516611

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.