ArticlePharmaceuticals (Basel, Switzerland)2026
Alkyl-Chain Extension and Terminal Amine Substitution Shape Cardiotoxic Profiles of Methylenedioxy Cathinones in Zebrafish Embryos.
Ouwais Aljabasini, Niki Tagkalidou, Martalu D Pazos, Guillermo García-Díez, Eva Prats, Roger Seco, Xavier Berzosa, Raúl López-Arnau, Demetrio Raldúa
Abstract read
In one paragraphArticle in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
9 authors.
Ouwais AljabasiniInstitute of Environmental Assessment and Water Research (IDAEA-CSIC), Jordi Girona, 18, 08034 Barcelona, Spain.
Niki TagkalidouInstitute of Environmental Assessment and Water Research (IDAEA-CSIC), Jordi Girona, 18, 08034 Barcelona, Spain.
Martalu D PazosDepartment of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, Pharmacology Section, Institute of Biomedicine (IBUB), University of Barcelona, 08028 Barcelona, Spain.ORCID 0000-0002-3138-1390 Guillermo García-DíezChemical Reactions for Innovative Solutions (CRISOL), IQS School of Engineering, Universitat Ramon Llull, 08017 Barcelona, Spain.
Roger SecoInstitute of Environmental Assessment and Water Research (IDAEA-CSIC), Jordi Girona, 18, 08034 Barcelona, Spain.ORCID 0000-0002-2078-9956 Xavier BerzosaChemical Reactions for Innovative Solutions (CRISOL), IQS School of Engineering, Universitat Ramon Llull, 08017 Barcelona, Spain.
Raúl López-ArnauDepartment of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, Pharmacology Section, Institute of Biomedicine (IBUB), University of Barcelona, 08028 Barcelona, Spain.ORCID 0000-0001-8904-7398 Demetrio RaldúaInstitute of Environmental Assessment and Water Research (IDAEA-CSIC), Jordi Girona, 18, 08034 Barcelona, Spain.ORCID 0000-0001-5256-1641 Funding
Government of Catalonia 2021SGR0090Government of Catalonia 2023 FISDU 00182Ministerio de Ciencia, Innovación y Universidades PID2022-137541OB-I00Ministerio de Ciencia, Innovación y Universidades PID2023-148502OB-C21Ministerio de Ciencia, Innovación y Universidades PREP2022-104748Ministerio de Ciencia, Innovación y Universidades PREP2023-001814Plan Nacional sobre Drogas 2024I057
6 · The paper itselfAbstract
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Indexed as
3,4-methylenedioxy cathinonesatrioventricular blockcardiotoxicitydipentylonemethyloneNew Approach Methodologiesnew psychoactive substancespentylonestructure-activity relationshipsynthetic cathinoneszebrafish embryo
Identifiers
PMID42653740
PMCPMC13516094
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