Evidence map›Paper›PMID 42653683›Full record

ReviewPharmaceuticals (Basel, Switzerland)2026

Pathological Allostery in ADAMTS13: Autoantibody-Induced Modulation and Its Role in Immune Thrombotic Thrombocytopenic Purpura (iTTP).

Madison Gil, Konstantine Halkidis

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Madison GilDepartment of Pathology and Laboratory Medicine, The University of Kansas Medical Center, Kansas City, KS 66160, USA.
Konstantine HalkidisDepartment of Pathology and Laboratory Medicine, The University of Kansas Medical Center, Kansas City, KS 66160, USA.ORCID 0000-0002-9594-1852

Funding

Exploring the mechanisms of action of anti-ADAMTS 13 antibodies in immune thrombotic thrombocytopenic purpuraK08HL163471 · NHLBI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Konstantine Halkidis · 2022 to 2026
$826k
American Heart Association 26BCDA1622687American Heart Association 26PRE1563350National Heart Lung and Blood Institute HL163471NHLBI NIH HHS K08 HL163471
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ADAMTS13allosteryantibodiesinhibitionmechanismthermodynamicsthrombotic thrombocytopenic purpura

Identifiers

PMID42653683
PMCPMC13516607

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.