Evidence map›Paper›PMID 42653677›Full record

ArticlePharmaceuticals (Basel, Switzerland)2026

Development and Validation of an LC-MS/MS Method for Simultaneous Quantification of Pazopanib, Cabozantinib, Sorafenib, Axitinib, Tivozanib, Sunitinib, and the Metabolites Sorafenib N-Oxide and Desethyl-Sunitinib in Human Plasma.

Eva Greibe, Jakob N Henriksen, Niels Fristrup, Elke Hoffmann-Lücke

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eva GreibeDepartment of Clinical Biochemistry, Aarhus University Hospital, 8200 Aarhus N, Denmark.
Jakob N HenriksenDepartment of Clinical Pharmacology, Aarhus University Hospital, 8200 Aarhus N, Denmark.ORCID 0000-0003-0784-3206
Niels FristrupDepartment of Clinical Pharmacology, Aarhus University Hospital, 8200 Aarhus N, Denmark.ORCID 0009-0006-4442-0535
Elke Hoffmann-LückeDepartment of Clinical Biochemistry, Aarhus University Hospital, 8200 Aarhus N, Denmark.ORCID 0000-0002-2437-0140

Funding

Department of Clinical Biochemistry, Aarhus University Hospital No grant numberThe Medicine Fund of the Danish Regions EMN-2019-01055
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

axitinibcabozantinibdesethyl-sunitinibpazopanibrenal cell carcinomasorafenibsorafenib N-oxidestabilitysunitinibtivozanibtyrosine kinase inhibitor

Identifiers

PMID42653677
PMCPMC13517061

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.