Evidence map›Paper›PMID 42653607›Full record

ArticleMicromachines2026

AC Electrokinetics-Enhanced Capacitive Aptasensor for Point-of-Care Testing of Acrylamide in Coffee.

Ke Wang, Mingna Xie, Yuyang Zhao, Jiuyi Wang, Leilei Zeng, Xiaogang Lin, Jie Jayne Wu

Abstract read
In one paragraph

Article in Micromachines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ke WangKey Laboratory of Optoelectronic Technology and Systems, Ministry of Education, Chongqing University, Chongqing, 400044, China.ORCID 0000-0003-2830-8480
Mingna XieKey Laboratory of Optoelectronic Technology and Systems, Ministry of Education, Chongqing University, Chongqing, 400044, China.
Yuyang ZhaoKey Laboratory of Optoelectronic Technology and Systems, Ministry of Education, Chongqing University, Chongqing, 400044, China.
Jiuyi WangKey Laboratory of Optoelectronic Technology and Systems, Ministry of Education, Chongqing University, Chongqing, 400044, China.
Leilei ZengKey Laboratory of Optoelectronic Technology and Systems, Ministry of Education, Chongqing University, Chongqing, 400044, China.
Xiaogang LinKey Laboratory of Optoelectronic Technology and Systems, Ministry of Education, Chongqing University, Chongqing, 400044, China.ORCID 0000-0001-9255-0672
Jie Jayne WuDepartment of Electrical Engineering and Computer Science, The University of Tennessee, Knoxville, TN 37996, USA.ORCID 0000-0001-5143-9425

Funding

the National foreign expert project No. S20240042
6 · The paper itself

Abstract

Acrylamide (AA) is a common contaminant in foods processed at high temperatures and has attracted significant attention due to its potential neurotoxicity and carcinogenicity. Therefore, the development of a highly sensitive, highly selective sensing technology suitable for on-site detection is of great importance for ensuring food safety. In this study, an aptamer (Apt)-based capacitive AA sensor was developed based on the alternating current electrokinetics (ACEK) effect. The sensor utilizes an aptamer as the biomimetic recognition element, which can specifically recognize AA, thereby enabling quantitative detection. Additionally, a detachable detection fixture and data acquisition system were designed to enhance the detection stability and convenience of sensor. Within the linear range of 1 nmol/L to 10 µmol/L, the sensor response (dC/dt) exhibited a good linear relationship with AA concentration, with a detection limit as low as 0.4235 nmol/L. The sensor exhibits good selectivity toward structural analogs of AA, with a recovery relative standard deviations (RSDs) of less than 5.42% in spiked coffee samples. This portable detection system provides a sensitive and user-friendly tool for the analysis of acrylamide in food and holds great potential for application in food safety.

Indexed as

acrylamidealternating current electrokinetics effectaptamercapacitive sensorpoint-of-care testing

Identifiers

PMID42653607
PMCPMC13515806

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.