ReviewMicromachines2026
Surface-Engineered Magnetic Nanoparticles in Skeletal Muscle Tissue Engineering: From Biological Interactions to Clinical Translation.
Review in Micromachines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The repair and functional restoration of skeletal muscle tissue following trauma, degenerative disease, or volumetric muscle loss remains a significant unmet clinical challenge in tissue engineering, where the need to recapitulate the anisotropic architecture, mechanical compliance, and high metabolic demands of native muscle imposes stringent requirements on biomaterial design. Traditional cell culturing and scaffold fabrication strategies have proven insufficient to address these demands in isolation, particularly in integrating mechanical integrity, biochemical functionality, and biological activity within a single biomaterial system. Recent advances in material science have accelerated the evolution of skeletal muscle tissue engineering toward a more precise and technologically sophisticated discipline. In this context, surface-engineered magnetic nanoparticle (MNP) hybrids have emerged as a promising multifunctional platform, owing to their intrinsic biocompatibility, tunable physicochemical properties, and rapid, non-invasive responsiveness to external magnetic fields. These unique characteristics have enabled the development of magnetic force-based tissue engineering strategies, facilitating controlled myogenic cell organization, magnetically guided delivery of therapeutic agents and stem cells, enhanced muscle construct formation within responsive scaffolds, and real-time non-invasive monitoring of engineered systems via MRI. This review systematically synthesizes the recent advances in surface-engineered MNP platforms for skeletal muscle tissue engineering, covering organic and inorganic coating strategies, magnetically responsive scaffold integration, guided cell and drug delivery, and construct monitoring, whilst critically appraising the biocompatibility, biodistribution, and regulatory challenges that currently define the translational pathway for MNP-augmented skeletal muscle constructs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.