Evidence map›Paper›PMID 42653482›Full record

ArticleInternational journal of molecular sciences2026

Distinct Inflammation-Associated Microbiome Signatures in Pediatric Non-IgE-Mediated Food Allergy.

Maria-Teodora Coșoreanu, Gratiela Gradisteanu Pircalabioru, Irina-Oana Lixandru-Petre, Mara-Ioana Ionescu, Andreea Ioan, Eliza-Elena Cinteză, Felicia Galoș

Abstract read
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Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Maria-Teodora CoșoreanuDepartment of Pediatrics, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Gratiela Gradisteanu PircalabioruFaculty of Biology, University of Bucharest, 030018 Bucharest, Romania.ORCID 0000-0002-6384-1822
Irina-Oana Lixandru-PetreeBio-Hub Centre of Excellence in Bioengineering, National University for Science and Technology, Politehnica Bucharest, 060042 Bucharest, Romania.
Mara-Ioana IonescuMarie Curie Emergency Children's Hospital, 041451 Bucharest, Romania.ORCID 0000-0001-9766-1558
Andreea IoanDepartment of Pediatrics, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0001-8628-3352
Eliza-Elena CintezăDepartment of Pediatrics, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0003-3239-0704
Felicia GaloșDepartment of Pediatrics, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Funding

HORIZON-WIDERA- 2022-TALENTS-01 grant agreement - 101087007 - eBio-hub
6 · The paper itself

Abstract

Non-IgE-mediated food allergy is characterized by delayed gastrointestinal manifestations and the absence of reliable non-invasive biomarkers. Increasing evidence suggests that gut microbiota may contribute to this disease pathogenesis. The aim of this study was to characterize the gut microbiome composition in thirty pediatric patients diagnosed with non-IgE-mediated food allergy, in comparison to fifteen healthy controls children, and to investigate its association with fecal calprotectin, eosinophil-derived neurotoxin (EDN) and IgA. Gut microbiota profiling was performed by 16S rRNA gene sequencing targeting the V3-V4 region. Compared with healthy controls, higher mean relative abundances of

Indexed as

Food HypersensitivityGastrointestinal MicrobiomeInflammationBacteriaBiomarkersChildChild, PreschoolEosinophil-Derived NeurotoxinFecesFemaleHumansImmunoglobulin AImmunoglobulin ELeukocyte L1 Antigen ComplexMaleRNA, Ribosomal, 16SBiomarkersEosinophil-Derived NeurotoxinImmunoglobulin AImmunoglobulin ELeukocyte L1 Antigen ComplexRNA, Ribosomal, 16S16S rRNA sequencingearly-life exposureseosinophil-derived neurotoxinfecal biomarkersfecal calprotectingut microbiomenon-IgE-mediated food allergy

Identifiers

PMID42653482
PMCPMC13513731

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.