Effects of Maternal Zinc Deficiency and Post-Weaning Zinc Status on Neuroendocrine Markers Associated with Pubertal Regulation in Female Rat Offspring.

Meltem Gumus, Buse Gunaydın-Turker, Nilufer Akgun-Unal, Elif Gulbahce-Mutlu, Saltuk Bugra Baltaci, Omer Unal, Rasim Mogulkoc, Abdulkerim Kasim Baltaci

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Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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5 · Who and what money

Authors and funding

8 authors.

Meltem GumusMedical Faculty, Department of Child Health and Diseases, Selcuk University, 42250 Konya, Türkiye.

Buse Gunaydın-TurkerMedical Faculty, Department of Physiology, Erciyes University, 38030 Kayseri, Türkiye.ORCID 0000-0003-2759-7495

Nilufer Akgun-UnalMedical Faculty, Department of Biophysics, Ondokuz Mayis University, 55139 Samsun, Türkiye.ORCID 0000-0001-7750-482X

Elif Gulbahce-MutluMedical Faculty, Department of Medical Biology, KTO Karatay University, 42020 Konya, Türkiye.ORCID 0000-0003-2391-2152

Saltuk Bugra BaltaciMedical Faculty, Department of Physiology, Istanbul Medipol University, 34810 Istanbul, Türkiye.ORCID 0000-0002-9752-7508

Omer UnalMedical Faculty, Department of Physiology, Samsun University, 55420 Samsun, Türkiye.ORCID 0000-0002-4816-830X

Rasim MogulkocMedical Faculty, Department of Physiology, Selcuk University, 42250 Konya, Türkiye.

Abdulkerim Kasim BaltaciMedical Faculty, Department of Physiology, Selcuk University, 42250 Konya, Türkiye.ORCID 0000-0003-2461-1212

Funding

Selçuk University 20202005

6 · The paper itself

Abstract

This study investigated the effects of maternal zinc deficiency and post-weaning zinc status on neuroendocrine markers associated with pubertal regulation in female rat offspring. A total of 40 female rats were divided into four groups: zinc deficiency (G1; MZD + ZD), standard diet (G2; MZD + SD), zinc supplementation (G3; MZD + ZnS), and control (G4; CON). Groups G1-G3 were obtained from mothers with zinc deficiency, while G4 was obtained from mothers fed a standard diet. The procedures lasted 45 days. GATAD1, kisspeptin, GnRH, and NPY gene expressions in hypothalamic tissues were analyzed by RT-PCR; serum kisspeptin, GnRH, FSH, LH, leptin, and NPY levels were analyzed by ELISA. The lowest GATAD1, kisspeptin, and NPY gene expressions were found in groups G1 and G2 (

Indexed as

Sexual MaturationZincAnimalsBiomarkersFemaleFollicle Stimulating HormoneGonadotropin-Releasing HormoneHypothalamusKisspeptinsLeptinLuteinizing HormoneNeuropeptide YRatsWeaningBiomarkersFollicle Stimulating HormoneGonadotropin-Releasing HormoneKisspeptinsLeptinLuteinizing HormoneNeuropeptide YZinchormonal parametershypothalamusmaternal zinc deficiencynutritionpubertyrat

Identifiers

PMID42653477

DOI10.3390/ijms27167479

PMCPMC13513261

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.