Evidence map›Paper›PMID 42653443›Full record

ArticleInternational journal of molecular sciences2026

Expression of

Agnieszka Kalita, Magdalena Sikora-Skrabaka, Karolina Gołąbek, Maria Dąbrowska, Joanna Katarzyna Strzelczyk, Dariusz Waniczek, Andrzej Witkoś, Ewa Nowakowska-Zajdel

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Agnieszka KalitaDepartment of Nutrition-Related Disease Prevention, Department of Metabolic Disease Prevention, Faculty of Public Health in Bytom, Medical University of Silesia in Katowice, 40-055 Katowice, Poland.ORCID 0000-0002-1065-4978
Magdalena Sikora-SkrabakaDepartment of Clinical Oncology, No. 4 Provincial Specialist Hospital, 41-902 Bytom, Poland.ORCID 0000-0003-1143-1423
Karolina GołąbekDepartment of Medical and Molecular Biology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 19 Jordana St., 41-808 Zabrze, Poland.ORCID 0000-0002-0042-5856
Maria DąbrowskaDepartment of Clinical Oncology, No. 4 Provincial Specialist Hospital, 41-902 Bytom, Poland.ORCID 0000-0001-9222-3399
Joanna Katarzyna StrzelczykDepartment of Medical and Molecular Biology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 19 Jordana St., 41-808 Zabrze, Poland.ORCID 0000-0002-3686-5685
Dariusz WaniczekDepartment of Oncological Surgery, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 41-514 Katowice, Poland.ORCID 0000-0002-0410-8604
Andrzej WitkośDepartment of Clinical Oncology, No. 4 Provincial Specialist Hospital, 41-902 Bytom, Poland.
Ewa Nowakowska-ZajdelDepartment of Nutrition-Related Disease Prevention, Department of Metabolic Disease Prevention, Faculty of Public Health in Bytom, Medical University of Silesia in Katowice, 40-055 Katowice, Poland.ORCID 0000-0003-3941-7308

Funding

Medical University of Silesia PCN-2-080/N/1/K, BNW-2-117/N/4/Z, BNW-1-111/K/5/Z, and BNW-1-133/K/4/2.
6 · The paper itself

Abstract

The role of adamalysins (ADAMs) has been widely described in many processes related to carcinogenesis, angiogenesis, inflammation, metastasis, and metabolic disorders. Despite numerous studies, their role in colorectal cancer (CRC) remains unclear. The aim of this study was to evaluate the expression of selected ADAM genes in colorectal cancer tissue and corresponding surgical margins. In addition, for a subgroup of patients, the expression of selected proteins from the ADAM family was assessed. The final study group consisted of 67 patients who underwent elective surgery for colorectal cancer. The relative expression of the

Indexed as

ADAM10 ProteinADAM12 ProteinADAM17 ProteinADAM ProteinsAmyloid Precursor Protein SecretasesColorectal NeoplasmsGene Expression Regulation, NeoplasticMembrane ProteinsAgedBiomarkers, TumorFemaleHumansMaleMiddle AgedADAM10 ProteinADAM10 protein, humanADAM12 ProteinADAM12 protein, humanADAM17 ProteinADAM28 protein, humanADAM ProteinsAmyloid Precursor Protein SecretasesBiomarkers, TumorMembrane ProteinsADAM10ADAM12ADAM17ADAM28colorectal cancergene expression

Identifiers

PMID42653443
PMCPMC13513945

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.